Spiking working-memory model with strong PV and SST inhibition (and disinhibito…

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  "doi": "10.1101/2020.02.11.944751",
  "pmid": null,
  "year": "2020",
  "claim": "Spiking working-memory model with strong PV and SST inhibition (and disinhibitory VIP gate) maintains stable temporal dynamics; VIP modulation switches WM into encoding mode.",
  "pmcid": null,
  "title": "Strong inhibitory signaling underlies stable temporal dynamics and working memory in spiking neural networks",
  "authors": "Kim R, Sejnowski TJ.",
  "journal": null,
  "cite_key": "Kim2020",
  "evidence": "Recurrent spiking PFC model with E/PV/SST/VIP populations; tested working memory robustness under VIP perturbations.",
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  "text_access": "abstract_only",
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  "replication_status": "replicated_independent",
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  "claim_source_sentence": "Dissecting our RNN model revealed strong inhibitory-to-inhibitory connections underlying a disinhibitory microcircuit as a critical component for long neuronal timescales and WM maintenance.",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2023.11.006",
    "10.1101/2025.05.13.653877",
    "10.1101/2024.09.30.615819",
    "10.1016/j.neuron.2018.03.037",
    "10.1162/netn_a_00427"
  ],
  "effect_size_source_sentence": null
}

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