Details
- scope
- spiking E/I network with multiple interneurons
- claim_text
- A model with feedforward and feedback inhibition by PV and SST/VIP populations modulates theta-gamma cross-frequency coupling, with disinhibitory VIP recruitment shifting coupling strength.
- section_id
- section_13
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-13-conclusion
- source_kind
- review_finding
- source_path
- evidence/section_13_evidence_package.json
- study_system
- spiking E/I network with multiple interneurons
- section_title
- Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
- evidence_summary
- Spiking E/I network with separate PV (feedforward) and SST+VIP (feedback) populations; parameter sweeps quantify CFC.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated_independent
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-13-conclusion
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- raw_fields
{ "n": null, "id": "cluster_11_finding_54", "doi": "10.1371/journal.pcbi.1013363", "pmid": "40802842", "year": "2025", "claim": "A model with feedforward and feedback inhibition by PV and SST/VIP populations modulates theta-gamma cross-frequency coupling, with disinhibitory VIP recruitment shifting coupling strength.", "pmcid": "PMC12393765", "title": "The role of feedforward and feedback inhibition in modulating theta-gamma cross-frequency interactions in neural circuits.", "authors": "Chalkiadakis D, Sánchez-Claros J, López-Madrona VJ, Canals S, Mirasso CR.", "journal": "PLoS computational biology", "cite_key": "Chalkiadakis2025b", "evidence": "Spiking E/I network with separate PV (feedforward) and SST+VIP (feedback) populations; parameter sweeps quantify CFC.", "effect_size": null, "text_access": "fulltext", "study_system": "spiking E/I network with multiple interneurons", "_source_cluster": "cluster_11_computational_models", "replication_status": "replicated_independent", "_source_cluster_index": 53, "claim_source_sentence": "Using previously acquired electrophysiological data from the hippocampus of rats freely navigating in a familiar environment or in a novel one, we show that CFD is dynamically regulated and linked to the frequency of the gamma band, as predicted by the model.", "replication_evidence_dois": [ "10.1016/j.neuron.2023.11.006", "10.1101/2025.05.13.653877", "10.1101/2024.09.30.615819", "10.1016/j.neuron.2018.03.037", "10.1162/netn_a_00427" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-625612fd621b" ]
- source_span
Using previously acquired electrophysiological data from the hippocampus of rats freely navigating in a familiar environment or in a novel one, we show that CFD is dynamically regulated and linked to the frequency of the gamma band, as predicted by the model.
- evidence_refs
[ { "ref": "paper:paper-625612fd621b" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }