Details
- scope
- mouse primary visual cortex, in vivo two-photon imaging
- claim_text
- Locomotion increases activity of VIP, SST, and PV interneurons during visual stimulation in V1, challenging the simple disinhibition model of locomotion-induced gain
- section_id
- section_07_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
- effect_size
- All three interneuron types increased activity during locomotion with visual stimulation; SST and excitatory neurons non-responsive in darkness
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-07
- source_kind
- review_finding
- source_path
- evidence/section_07_evidence_package.json
- source_span
- We reveal that locomotion increases the activity of vasoactive intestinal peptide (VIP), somatostatin (SST) and parvalbumin (PV)-positive interneurons during visual stimulation, challenging the disinhibition model.
- study_system
- mouse primary visual cortex, in vivo two-photon imaging
- section_title
- Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward
- evidence_summary
- In vivo two-photon calcium imaging in layers 2/3 and 4 of mouse V1 during locomotion and visual stimulation
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- single study
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-07
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.7554/elife.14985", "claim": "Locomotion increases activity of VIP, SST, and PV interneurons during visual stimulation in V1, challenging the simple disinhibition model of locomotion-induced gain", "evidence": "In vivo two-photon calcium imaging in layers 2/3 and 4 of mouse V1 during locomotion and visual stimulation", "effect_size": "All three interneuron types increased activity during locomotion with visual stimulation; SST and excitatory neurons non-responsive in darkness", "text_access": "fulltext", "study_system": "mouse primary visual cortex, in vivo two-photon imaging", "replication_status": "single study", "claim_source_sentence": "We reveal that locomotion increases the activity of vasoactive intestinal peptide (VIP), somatostatin (SST) and parvalbumin (PV)-positive interneurons during visual stimulation, challenging the disinhibition model.", "replication_evidence_dois": [], "effect_size_source_sentence": "In darkness, while most VIP and PV neurons remained locomotion responsive, SST and excitatory neurons were largely non-responsive." }- source_refs
[ "paper:paper-acf576c0a2ed" ]
- evidence_refs
[ { "ref": "paper:paper-acf576c0a2ed" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }