Details

scope
rodent neocortex (review)
claim_text
Tremblay, Lee, & Rudy (2016) reviewed that the 5HT3aR interneuron group is divided into two subgroups based on VIP expression, with VIP+ neurons constituting ~40% of 5HT3aR INs and being entirely absent from PV or Sst populations.
section_id
section_01
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-01-introduction
source_kind
review_finding
source_path
evidence/section_01_evidence_package.json
source_span
The 5HT3aR group can be divided in two subgroups based on whether or not a 5HT3aR IN expresses vasointestinal pepetide (Vip), which is found in about 40 % of all 5HT3aR INs and is not expressed in PV or Sst neurons (Lee et al., 2010).
study_system
rodent neocortex (review)
section_title
Introduction
evidence_summary
Review consolidating immunohistochemical and Cre-line evidence: VIP neurons account for ~40% of 5HT3aR+ interneurons; PV/SST/VIP segregation is mutually exclusive at the major-class level.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-01-introduction
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.neuron.2016.06.033",
  "claim": "Tremblay, Lee, & Rudy (2016) reviewed that the 5HT3aR interneuron group is divided into two subgroups based on VIP expression, with VIP+ neurons constituting ~40% of 5HT3aR INs and being entirely absent from PV or Sst populations.",
  "title": null,
  "cite_key": "Tremblay2016",
  "evidence": "Review consolidating immunohistochemical and Cre-line evidence: VIP neurons account for ~40% of 5HT3aR+ interneurons; PV/SST/VIP segregation is mutually exclusive at the major-class level.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "rodent neocortex (review)",
  "target_section": "section_02",
  "_source_cluster": "cluster_01_molecular_taxonomy",
  "replication_status": "replicated",
  "_source_cluster_index": 19,
  "claim_source_sentence": "The 5HT3aR group can be divided in two subgroups based on whether or not a 5HT3aR IN expresses vasointestinal pepetide (Vip), which is found in about 40 % of all 5HT3aR INs and is not expressed in PV or Sst neurons (Lee et al., 2010)."
}
source_refs
[
  "paper:paper-53c8505de50f"
]
evidence_refs
[
  {
    "ref": "paper:paper-53c8505de50f"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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