Details
- scope
- review of rat S1 (Cauli 2004)
- section_id
- section_05
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
- effect_size
- single-cell sufficient to dilate arterioles
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-05-electrophysiology
- source_kind
- review_finding
- source_path
- evidence/section_05_evidence_package.json
- source_span
- It has been shown however, that Vip INs release Vip, a potent vasodilator, and that single cell stimulation of Vip+ bipolar neurons is sufficient to elicit vasodilatation of nearby arterioles.
- study_system
- review of rat S1 (Cauli 2004)
- section_title
- Intrinsic Electrophysiology
- evidence_summary
- Cauli 2004 single-cell stim + arteriole imaging (cited in Tremblay 2016)
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-05-electrophysiology
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- claim_text
Beyond fast inhibition, single Vip+ bipolar neurons are functionally pleiotropic: stimulation of a single Vip+ bipolar cell is sufficient to evoke vasodilatation of nearby arterioles (via VIP peptide release acting on local vasculature), placing the VIP class at the intersection of cortical disinhibition and neurovascular coupling — a peptidergic effect downstream of intrinsic firing.
- raw_fields
{ "n": null, "doi": "10.1016/j.neuron.2016.06.033", "claim": "Beyond fast inhibition, single Vip+ bipolar neurons are functionally pleiotropic: stimulation of a single Vip+ bipolar cell is sufficient to evoke vasodilatation of nearby arterioles (via VIP peptide release acting on local vasculature), placing the VIP class at the intersection of cortical disinhibition and neurovascular coupling — a peptidergic effect downstream of intrinsic firing.", "title": null, "cite_key": "Tremblay2016", "evidence": "Cauli 2004 single-cell stim + arteriole imaging (cited in Tremblay 2016)", "effect_size": "single-cell sufficient to dilate arterioles", "text_access": "fulltext", "study_system": "review of rat S1 (Cauli 2004)", "_source_cluster": "cluster_04_intrinsic_electrophysiology", "replication_status": "replication_unknown", "_source_cluster_index": 90, "claim_source_sentence": "It has been shown however, that Vip INs release Vip, a potent vasodilator, and that single cell stimulation of Vip+ bipolar neurons is sufficient to elicit vasodilatation of nearby arterioles.", "replication_evidence_dois": [], "effect_size_source_sentence": "single cell stimulation of Vip+ bipolar neurons is sufficient to elicit vasodilatation of nearby arterioles." }- source_refs
[ "paper:paper-53c8505de50f" ]
- evidence_refs
[ { "ref": "paper:paper-53c8505de50f" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }