Synaptic Properties and Connectivity

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Synaptic Properties and Connectivity

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Source: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/content/06_synaptic_properties.md

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  • 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...

  • 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...

  • 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...

  • 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...

  • 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...

  • 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...

  • 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference A note on scope. This section concentrates on cortical (V1, A1, S1, mPFC, motor cortex) and hippocampal VIP populations, where the modulator-targeted disinhibitory architecture has been most thoroughly dissected. Subcortical and amygdalar VIP-cell populations are referenced where they bear directly on the cortical disinhibitory motif (in particular for amygdalar fear-conditioning circuits) but are not surveyed exhau...

  • 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference A note on scope. This section concentrates on cortical (V1, A1, S1, mPFC, motor cortex) and hippocampal VIP populations, where the modulator-targeted disinhibitory architecture has been most thoroughly dissected. Subcortical and amygdalar VIP-cell populations are referenced where they bear directly on the cortical disinhibitory motif (in particular for amygdalar fear-conditioning circuits) but are not surveyed exhau...

  • 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference A note on scope. This section concentrates on cortical (V1, A1, S1, mPFC, motor cortex) and hippocampal VIP populations, where the modulator-targeted disinhibitory architecture has been most thoroughly dissected. Subcortical and amygdalar VIP-cell populations are referenced where they bear directly on the cortical disinhibitory motif (in particular for amygdalar fear-conditioning circuits) but are not surveyed exhau...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference0 A note on scope. This section concentrates on cortical (V1, A1, S1, mPFC, motor cortex) and hippocampal VIP populations, where the modulator-targeted disinhibitory architecture has been most thoroughly dissected. Subcortical and amygdalar VIP-cell populations are referenced where they bear directly on the cortical disinhibitory motif (in particular for amygdalar fear-conditioning circuits) but are not surveyed exhau...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference1 A note on scope. This section concentrates on cortical (V1, A1, S1, mPFC, motor cortex) and hippocampal VIP populations, where the modulator-targeted disinhibitory architecture has been most thoroughly dissected. Subcortical and amygdalar VIP-cell populations are referenced where they bear directly on the cortical disinhibitory motif (in particular for amygdalar fear-conditioning circuits) but are not surveyed exhau...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference2 A note on scope. This section concentrates on cortical (V1, A1, S1, mPFC, motor cortex) and hippocampal VIP populations, where the modulator-targeted disinhibitory architecture has been most thoroughly dissected. Subcortical and amygdalar VIP-cell populations are referenced where they bear directly on the cortical disinhibitory motif (in particular for amygdalar fear-conditioning circuits) but are not surveyed exhau...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference3 A note on scope. This section concentrates on cortical (V1, A1, S1, mPFC, motor cortex) and hippocampal VIP populations, where the modulator-targeted disinhibitory architecture has been most thoroughly dissected. Subcortical and amygdalar VIP-cell populations are referenced where they bear directly on the cortical disinhibitory motif (in particular for amygdalar fear-conditioning circuits) but are not surveyed exhau...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference4 A note on scope. This section concentrates on cortical (V1, A1, S1, mPFC, motor cortex) and hippocampal VIP populations, where the modulator-targeted disinhibitory architecture has been most thoroughly dissected. Subcortical and amygdalar VIP-cell populations are referenced where they bear directly on the cortical disinhibitory motif (in particular for amygdalar fear-conditioning circuits) but are not surveyed exhau...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference5 Within a cortical column, VIP interneurons receive excitatory drive from neighbouring pyramidal neurons that is, by paired-recording standards, modest. Connection probabilities from local L2/3 pyramidal cells onto VIP cells are comparable to (and in some preparations slightly lower than) those onto SST and PV interneurons 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference6, and unitary EPSC amplitudes are correspondingly small [Karnani2016a, Walker2016...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference7 Within a cortical column, VIP interneurons receive excitatory drive from neighbouring pyramidal neurons that is, by paired-recording standards, modest. Connection probabilities from local L2/3 pyramidal cells onto VIP cells are comparable to (and in some preparations slightly lower than) those onto SST and PV interneurons 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference8, and unitary EPSC amplitudes are correspondingly small [Karnani2016a, Walker2016...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference9 Within a cortical column, VIP interneurons receive excitatory drive from neighbouring pyramidal neurons that is, by paired-recording standards, modest. Connection probabilities from local L2/3 pyramidal cells onto VIP cells are comparable to (and in some preparations slightly lower than) those onto SST and PV interneurons 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference0, and unitary EPSC amplitudes are correspondingly small [Karnani2016a, Walker2016...

  • 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference1 Within a cortical column, VIP interneurons receive excitatory drive from neighbouring pyramidal neurons that is, by paired-recording standards, modest. Connection probabilities from local L2/3 pyramidal cells onto VIP cells are comparable to (and in some preparations slightly lower than) those onto SST and PV interneurons 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference2, and unitary EPSC amplitudes are correspondingly small [Karnani2016a, Walker2016...

  • 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference3 Within a cortical column, VIP interneurons receive excitatory drive from neighbouring pyramidal neurons that is, by paired-recording standards, modest. Connection probabilities from local L2/3 pyramidal cells onto VIP cells are comparable to (and in some preparations slightly lower than) those onto SST and PV interneurons 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference4, and unitary EPSC amplitudes are correspondingly small [Karnani2016a, Walker2016...

  • 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference5 Within a cortical column, VIP interneurons receive excitatory drive from neighbouring pyramidal neurons that is, by paired-recording standards, modest. Connection probabilities from local L2/3 pyramidal cells onto VIP cells are comparable to (and in some preparations slightly lower than) those onto SST and PV interneurons 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference6, and unitary EPSC amplitudes are correspondingly small [Karnani2016a, Walker2016...

  • 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference7 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference8. PV cells contribute a smaller but non-negligible f...

  • 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference9 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference0. PV cells contribute a smaller but non-negligible f...

  • 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference1 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference2. PV cells contribute a smaller but non-negligible f...

  • 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference3 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference4. PV cells contribute a smaller but non-negligible f...

  • 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference5 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference6. PV cells contribute a smaller but non-negligible f...

  • 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference7 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference8. PV cells contribute a smaller but non-negligible f...

  • 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference9 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference0. PV cells contribute a smaller but non-negligible f...

  • 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference1 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference2. PV cells contribute a smaller but non-negligible f...

  • 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference3 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference4. PV cells contribute a smaller but non-negligible f...

  • 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference5 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference6. PV cells contribute a smaller but non-negligible f...

  • 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference7 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference8. PV cells contribute a smaller but non-negligible f...

  • 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference9 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference0. PV cells contribute a smaller but non-negligible f...

  • 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference1 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference2. PV cells contribute a smaller but non-negligible f...

  • 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference3 Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference4. PV cells contribute a smaller but non-negligible f...

  • 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference5 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference6, 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference7, 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference8, 6Citationpaper:paper-f02f24cb44ffThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference9, 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference0, 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference1, 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference2, 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference3, 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference4, [A...

  • 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference5 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference6, 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference7, 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference8, 7Citationpaper:paper-d405e5906927The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference9, 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference0, 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference1, 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference2, 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference3, 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference4, [A...

  • 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference5 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference6, 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference7, 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference8, 4Citationpaper:paper-1659c2dc5d60The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference9, 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference0, 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference1, 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference2, 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference3, 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference4, [A...

  • 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference5 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference6, 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference7, 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference8, 5Citationpaper:paper-065a0eae69a5The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference9, 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference0, 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference1, 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference2, 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference3, 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference4, [A...

  • 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference5 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference6, 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference7, 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference8, 1Citationpaper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356dThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference9, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference00, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference01, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference02, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference03, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference04, [A...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference05 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference06, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference07, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference08, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference09, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference10, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference11, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference12, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference13, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference14, [A...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference15 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference16, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference17, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference18, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference19, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference20, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference21, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference22, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference23, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference24, [A...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference25 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference26, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference27, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference28, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference29, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference30, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference31, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference32, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference33, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference34, [A...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference35 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference36, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference37, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference38, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference39, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference40, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference41, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference42, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference43, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference44, [A...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference45 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference46, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference47, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference48, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference49, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference50, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference51, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference52, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference53, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference54, [A...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference55 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference56, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference57, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference58, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference59, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference60, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference61, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference62, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference63, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference64, [A...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference65 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference66, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference67, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference68, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference69, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference70, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference71, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference72, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference73, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference74, [A...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference75 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference76, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference77, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference78, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference79, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference80, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference81, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference82, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference83, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference84, [A...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference85 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference86, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference87, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference88, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference89, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference90, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference91, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference92, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference93, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference94, [A...

  • 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference95 VIP synaptic connectivity at a glance. (A) Qualitative cross-study consensus categories (absent / weak / moderate / strong) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference96, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference97, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference98, 2Citationpaper:paper-d1988cf656c2The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference99, 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference00, 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference01, 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference02, 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference03, 3Citationpaper:paper-7227d2a3ed3eThe preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}sec-molecular-identity through {ref}sec-morphology) through their intrinsic and morphological signatures ({ref}sec-electrophysiology). Those analyses establish what kind of cell a VIP interneuron is; they do not yet tell us what circuit role it plays. That role is set by synapses — by the afferents that drive VIP...content/06_synaptic_properties.md:line 5Open reference04, [A...

  • ... 414 additional anchors in refs_json

References

  1. [Yu2019] paper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356d “The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}`sec-molecular-identity` through {ref}`sec-morphology`) through their intrinsic and morphological signatures ({ref}`sec-electrophysiology`). Those analyses establish *what kind of cell* a VIP interneuron is; they do not yet tell us *what circuit role it plays*. That role is set by synapses — by the afferents that drive VIP...”
  2. [Zhou2017] paper:paper-d1988cf656c2 “The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}`sec-molecular-identity` through {ref}`sec-morphology`) through their intrinsic and morphological signatures ({ref}`sec-electrophysiology`). Those analyses establish *what kind of cell* a VIP interneuron is; they do not yet tell us *what circuit role it plays*. That role is set by synapses — by the afferents that drive VIP...”
  3. [Anastasiades2021a] paper:paper-7227d2a3ed3e “The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}`sec-molecular-identity` through {ref}`sec-morphology`) through their intrinsic and morphological signatures ({ref}`sec-electrophysiology`). Those analyses establish *what kind of cell* a VIP interneuron is; they do not yet tell us *what circuit role it plays*. That role is set by synapses — by the afferents that drive VIP...”
  4. [Pfeffer2013] paper:paper-1659c2dc5d60 “The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}`sec-molecular-identity` through {ref}`sec-morphology`) through their intrinsic and morphological signatures ({ref}`sec-electrophysiology`). Those analyses establish *what kind of cell* a VIP interneuron is; they do not yet tell us *what circuit role it plays*. That role is set by synapses — by the afferents that drive VIP...”
  5. [Pi2013] paper:paper-065a0eae69a5 “The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}`sec-molecular-identity` through {ref}`sec-morphology`) through their intrinsic and morphological signatures ({ref}`sec-electrophysiology`). Those analyses establish *what kind of cell* a VIP interneuron is; they do not yet tell us *what circuit role it plays*. That role is set by synapses — by the afferents that drive VIP...”
  6. [Lee2013] paper:paper-f02f24cb44ff “The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}`sec-molecular-identity` through {ref}`sec-morphology`) through their intrinsic and morphological signatures ({ref}`sec-electrophysiology`). Those analyses establish *what kind of cell* a VIP interneuron is; they do not yet tell us *what circuit role it plays*. That role is set by synapses — by the afferents that drive VIP...”
  7. [Karnani2016a] paper:paper-d405e5906927 “The preceding sections traced VIP interneurons from their lineage and molecular identity ({ref}`sec-molecular-identity` through {ref}`sec-morphology`) through their intrinsic and morphological signatures ({ref}`sec-electrophysiology`). Those analyses establish *what kind of cell* a VIP interneuron is; they do not yet tell us *what circuit role it plays*. That role is set by synapses — by the afferents that drive VIP...”
  8. [Walker2016] paper:paper-e93955349823 “A note on scope. This section concentrates on cortical (V1, A1, S1, mPFC, motor cortex) and hippocampal VIP populations, where the modulator-targeted disinhibitory architecture has been most thoroughly dissected. Subcortical and amygdalar VIP-cell populations are referenced where they bear directly on the cortical disinhibitory motif (in particular for amygdalar fear-conditioning circuits) but are not surveyed exhau...”
  9. [Wall2016] paper:paper-32a4e1ae2010 “A note on scope. This section concentrates on cortical (V1, A1, S1, mPFC, motor cortex) and hippocampal VIP populations, where the modulator-targeted disinhibitory architecture has been most thoroughly dissected. Subcortical and amygdalar VIP-cell populations are referenced where they bear directly on the cortical disinhibitory motif (in particular for amygdalar fear-conditioning circuits) but are not surveyed exhau...”
  10. [Pronneke2015] paper:paper-8e91417bef90 “Within a cortical column, VIP interneurons receive excitatory drive from neighbouring pyramidal neurons that is, by paired-recording standards, modest. Connection probabilities from local L2/3 pyramidal cells onto VIP cells are comparable to (and in some preparations slightly lower than) those onto SST and PV interneurons [Karnani2016a], and unitary EPSC amplitudes are correspondingly small [Karnani2016a, Walker2016...”
  11. [Cauli2014] paper:paper-ba54efae783d “Within a cortical column, VIP interneurons receive excitatory drive from neighbouring pyramidal neurons that is, by paired-recording standards, modest. Connection probabilities from local L2/3 pyramidal cells onto VIP cells are comparable to (and in some preparations slightly lower than) those onto SST and PV interneurons [Karnani2016a], and unitary EPSC amplitudes are correspondingly small [Karnani2016a, Walker2016...”
  12. [Pronneke2019] paper:paper-51004efbc353 “Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations [Pfeffer2013, Karnani2016a, Walker2016]. PV cells contribute a smaller but non-negligible f...”
  13. [Karnani2016b] paper:paper-0a3cf7627c63 “Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations [Pfeffer2013, Karnani2016a, Walker2016]. PV cells contribute a smaller but non-negligible f...”
  14. [Sabri2024] paper:paper-5c93ed95f704 “Local inhibition onto VIP cells is, conversely, dominated by SST input. Paired recordings and SST-Cre optogenetics consistently show that SST interneurons provide the largest single source of local IPSCs onto VIP cells, with connection probabilities that meet or exceed the reciprocal VIP→SST direction in the same preparations [Pfeffer2013, Karnani2016a, Walker2016]. PV cells contribute a smaller but non-negligible f...”
  15. [Zhang2014] paper:paper-05bd6c97da43 “**VIP synaptic connectivity at a glance.** **(A)** Qualitative cross-study consensus categories (`absent / weak / moderate / strong`) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include [Karnani2016a], [Walker2016], [Karnani2016a], [Wall2016], [Lee2013], [Zhang2014], [Williams2019], [Cruikshank2012], [Anastasiades2021a], [A...”
  16. [Williams2019] paper:paper-55f18434021b “**VIP synaptic connectivity at a glance.** **(A)** Qualitative cross-study consensus categories (`absent / weak / moderate / strong`) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include [Karnani2016a], [Walker2016], [Karnani2016a], [Wall2016], [Lee2013], [Zhang2014], [Williams2019], [Cruikshank2012], [Anastasiades2021a], [A...”
  17. [Cruikshank2012] paper:paper-49604016d900 “**VIP synaptic connectivity at a glance.** **(A)** Qualitative cross-study consensus categories (`absent / weak / moderate / strong`) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include [Karnani2016a], [Walker2016], [Karnani2016a], [Wall2016], [Lee2013], [Zhang2014], [Williams2019], [Cruikshank2012], [Anastasiades2021a], [A...”
  18. [Audette2018] paper:paper-9a47e0f1c3a7 “**VIP synaptic connectivity at a glance.** **(A)** Qualitative cross-study consensus categories (`absent / weak / moderate / strong`) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include [Karnani2016a], [Walker2016], [Karnani2016a], [Wall2016], [Lee2013], [Zhang2014], [Williams2019], [Cruikshank2012], [Anastasiades2021a], [A...”
  19. [Porter1999] paper:paper-5f194b747ea7 “**VIP synaptic connectivity at a glance.** **(A)** Qualitative cross-study consensus categories (`absent / weak / moderate / strong`) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include [Karnani2016a], [Walker2016], [Karnani2016a], [Wall2016], [Lee2013], [Zhang2014], [Williams2019], [Cruikshank2012], [Anastasiades2021a], [A...”
  20. [Fu2014] paper:paper-5cfe39bf225d “**VIP synaptic connectivity at a glance.** **(A)** Qualitative cross-study consensus categories (`absent / weak / moderate / strong`) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include [Karnani2016a], [Walker2016], [Karnani2016a], [Wall2016], [Lee2013], [Zhang2014], [Williams2019], [Cruikshank2012], [Anastasiades2021a], [A...”
  21. [Arroyo2012] paper:paper-7ada22e6c011 “**VIP synaptic connectivity at a glance.** **(A)** Qualitative cross-study consensus categories (`absent / weak / moderate / strong`) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include [Karnani2016a], [Walker2016], [Karnani2016a], [Wall2016], [Lee2013], [Zhang2014], [Williams2019], [Cruikshank2012], [Anastasiades2021a], [A...”
  22. [Ferezou2002] paper:paper-1fd860b6dd41 “**VIP synaptic connectivity at a glance.** **(A)** Qualitative cross-study consensus categories (`absent / weak / moderate / strong`) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include [Karnani2016a], [Walker2016], [Karnani2016a], [Wall2016], [Lee2013], [Zhang2014], [Williams2019], [Cruikshank2012], [Anastasiades2021a], [A...”
  23. [Vucurovic2010] paper:paper-0336a131683f “**VIP synaptic connectivity at a glance.** **(A)** Qualitative cross-study consensus categories (`absent / weak / moderate / strong`) for afferent drive onto VIP, SST and PV interneurons. Six afferent classes are pooled across rodent neocortex (V1, A1, S1, mPFC). Sources include [Karnani2016a], [Walker2016], [Karnani2016a], [Wall2016], [Lee2013], [Zhang2014], [Williams2019], [Cruikshank2012], [Anastasiades2021a], [A...”

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