Different Pvalb transcriptomic types preferentially target specific cortical la…

Details

scope: mouse visual cortex
claim_text: Different Pvalb transcriptomic types preferentially target specific cortical layers: Pvalb Tpbg in L2/3, Pvalb Reln Itm2a in L2/3-L4, and Pvalb Sema3e Kank4 and Pvalb Gabrg1 in L5-L6.
section_id: section_02_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
effect_size: 4+ layer-specific Pvalb t-types identified
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-02
source_kind: review_finding
source_path: evidence/section_02_evidence_package.json
source_span: the Pvalb subclass had t-types that predominantly targeted L2/3 (Pvalb Tpbg), L2/3 and L4 (Pvalb Reln Itm2a), and L5 and L6 (Pvalb Sema3e Kank4, Pvalb Gabrg1).
study_system: mouse visual cortex
section_title: Molecular Identity and Transcriptomic Taxonomy
evidence_summary
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-02
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 4200,
  "doi": "10.1016/j.cell.2020.09.057",
  "claim": "Different Pvalb transcriptomic types preferentially target specific cortical layers: Pvalb Tpbg in L2/3, Pvalb Reln Itm2a in L2/3-L4, and Pvalb Sema3e Kank4 and Pvalb Gabrg1 in L5-L6.",
  "evidence": "",
  "effect_size": "4+ layer-specific Pvalb t-types identified",
  "text_access": "fulltext",
  "study_system": "mouse visual cortex",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "the Pvalb subclass had t-types that predominantly targeted L2/3 (Pvalb Tpbg), L2/3 and L4 (Pvalb Reln Itm2a), and L5 and L6 (Pvalb Sema3e Kank4, Pvalb Gabrg1).",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "the Pvalb subclass had t-types that predominantly targeted L2/3 (Pvalb Tpbg), L2/3 and L4 (Pvalb Reln Itm2a), and L5 and L6 (Pvalb Sema3e Kank4, Pvalb Gabrg1)."
}

source_refs

[
  "paper:paper-pm-33186530"
]

evidence_refs

[
  {
    "ref": "paper:paper-pm-33186530"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Different Pvalb transcriptomic types preferentially target specific cortical la…

Details

Replication

Discussion