Details

scope
mouse VISp + ALM Patch-seq; transcriptomic taxonomy
claim_text
In mouse VISp, the GABAergic taxonomy comprises four classical subclasses (Pvalb, Sst, Vip, Htr3a+/Vip-) plus an additional Sncg subclass that transcriptomically bridges Vip and Lamp5 (renamed from Htr3a+/Vip-).
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
effect_size
5 GABAergic subclasses identified (Pvalb, Sst, Vip, Lamp5, Sncg)
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-05-electrophysiology
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
study_system
mouse VISp + ALM Patch-seq; transcriptomic taxonomy
section_title
Intrinsic Electrophysiology
evidence_summary
Patch-seq + scRNA-seq integration across VISp and ALM, n=2,955 cells with consistent t-type assignment
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-05-electrophysiology
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
raw_fields
{
  "n": 2955,
  "doi": "10.1016/j.cell.2020.09.057",
  "claim": "In mouse VISp, the GABAergic taxonomy comprises four classical subclasses (Pvalb, Sst, Vip, Htr3a+/Vip-) plus an additional Sncg subclass that transcriptomically bridges Vip and Lamp5 (renamed from Htr3a+/Vip-).",
  "title": null,
  "cite_key": "Gouwens2020a",
  "evidence": "Patch-seq + scRNA-seq integration across VISp and ALM, n=2,955 cells with consistent t-type assignment",
  "effect_size": "5 GABAergic subclasses identified (Pvalb, Sst, Vip, Lamp5, Sncg)",
  "text_access": "fulltext",
  "study_system": "mouse VISp + ALM Patch-seq; transcriptomic taxonomy",
  "_source_cluster": "cluster_04_intrinsic_electrophysiology",
  "replication_status": "replicated",
  "_source_cluster_index": 27,
  "claim_source_sentence": "Our recent single-cell transcriptomic study of two mouse cortical areas (Tasic et al., 2018), VISp and anterolateral motor cortex (ALM), confirmed these four major subclasses and revealed an additional subclass (Sncg) that is related to the Vip and Htr3a+/Vip-(renamed to Lamp5) subclasses.",
  "replication_evidence_dois": [
    "10.1038/s41586-021-03950-0",
    "10.1038/s41586-021-03465-8"
  ],
  "effect_size_source_sentence": "Our recent single-cell transcriptomic study of two mouse cortical areas (Tasic et al., 2018), VISp and anterolateral motor cortex (ALM), confirmed these four major subclasses and revealed an additional subclass (Sncg) that is related to the Vip and Htr3a+/Vip-(renamed to Lamp5) subclasses."
}
source_refs
[
  "paper:paper-pm-33186530"
]
source_span
Our recent single-cell transcriptomic study of two mouse cortical areas (Tasic et al., 2018), VISp and anterolateral motor cortex (ALM), confirmed these four major subclasses and revealed an additional subclass (Sncg) that is related to the Vip and Htr3a+/Vip-(renamed to Lamp5) subclasses.
evidence_refs
[
  {
    "ref": "paper:paper-pm-33186530"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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