Gouwens et al. (2020) defined 28 morphoelectric-transcriptomic (MET) types of c…

Details

scope: mouse VISp; Patch-seq (transcriptomics + ephys + morphology)
claim_text: Gouwens et al. (2020) defined 28 morphoelectric-transcriptomic (MET) types of cortical GABAergic interneurons through Patch-seq integration, providing a unified framework that reconciles ~60 t-types with ~26 me-types.
section_id: section_01
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json
review_repo: ComputationalReviewVIP
section_ref: wiki_page:computationalreviewvip-01-introduction
source_kind: review_finding
source_path: evidence/section_01_evidence_package.json
source_span: Through multimodal integrated analysis we define 28 met-types that have congruent morphological, electrophysiological, and transcriptomic properties and robust mutual predictability.
study_system: mouse VISp; Patch-seq (transcriptomics + ephys + morphology)
section_title: Introduction
evidence_summary: Patch-seq on 4,200+ cortical GABAergic neurons (mouse VISp); integrative classification yielded 28 MET-types; Vip subclass split into multiple MET-types defined by congruent morphology, electrophysiology, and t-type.
review_bundle_ref: analysis_bundle:ab-2ce40c33e827
replication_status: replicated
review_package_ref: analysis_bundle:ab-2ce40c33e827
source_artifact_ref: wiki_page:computationalreviewvip-01-introduction
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json
commit_sha: 95e761177f7d2ec565983d3307c14ec238f9677c
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP

Raw fields (4)

raw_fields

{
  "n": 4200,
  "doi": "10.1016/j.cell.2020.09.057",
  "claim": "Gouwens et al. (2020) defined 28 morphoelectric-transcriptomic (MET) types of cortical GABAergic interneurons through Patch-seq integration, providing a unified framework that reconciles ~60 t-types with ~26 me-types.",
  "title": null,
  "cite_key": "Gouwens2020a",
  "evidence": "Patch-seq on 4,200+ cortical GABAergic neurons (mouse VISp); integrative classification yielded 28 MET-types; Vip subclass split into multiple MET-types defined by congruent morphology, electrophysiology, and t-type.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "mouse VISp; Patch-seq (transcriptomics + ephys + morphology)",
  "target_section": "section_11",
  "_source_cluster": "cluster_01_molecular_taxonomy",
  "replication_status": "replicated",
  "_source_cluster_index": 15,
  "claim_source_sentence": "Through multimodal integrated analysis we define 28 met-types that have congruent morphological, electrophysiological, and transcriptomic properties and robust mutual predictability."
}

source_refs

[
  "paper:paper-pm-33186530"
]

evidence_refs

[
  {
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  }
]

source_policy

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Gouwens et al. (2020) defined 28 morphoelectric-transcriptomic (MET) types of c…

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Replication

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