Details

scope
mouse VISp; patch-seq
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
effect_size
5 Vip MET-types; Vip-MET-1 regular sustained, Vip-MET-2 irregular, Vip-MET-4/5 elevated sag
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-05-electrophysiology
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
We identified five Vip met-types ( Figure 7I – L ), all resembling bipolar or bitufted cells.
study_system
mouse VISp; patch-seq
section_title
Intrinsic Electrophysiology
evidence_summary
patch-seq + morphology; community detection on probabilistic mapping (Gouwens 2020)
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
novel
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-05-electrophysiology
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
The Vip subclass partitions into 5 MET-types in mouse VISp (Vip-MET-1 through Vip-MET-5) — all resembling bipolar or bitufted cells but with distinct intrinsic-firing fingerprints: Vip-MET-1 fires regular sustained spikes (Npy+, L2/3-L4), Vip-MET-2 fires irregularly (Ptprt+/Rspo1+, L2/3-L4), Vip-MET-4 shows irregular/transient firing with high hyperpolarization-evoked sag (lower L2/3), and Vip-MET-5 (Crispld2 Htr2c / Crispld2 Kcne4 t-types) innervates all layers including L1 with similarly elevated sag.
raw_fields
{
  "n": null,
  "doi": "10.1016/j.cell.2020.09.057",
  "claim": "The Vip subclass partitions into 5 MET-types in mouse VISp (Vip-MET-1 through Vip-MET-5) — all resembling bipolar or bitufted cells but with distinct intrinsic-firing fingerprints: Vip-MET-1 fires regular sustained spikes (Npy+, L2/3-L4), Vip-MET-2 fires irregularly (Ptprt+/Rspo1+, L2/3-L4), Vip-MET-4 shows irregular/transient firing with high hyperpolarization-evoked sag (lower L2/3), and Vip-MET-5 (Crispld2 Htr2c / Crispld2 Kcne4 t-types) innervates all layers including L1 with similarly elevated sag.",
  "title": null,
  "cite_key": "Gouwens2020a",
  "evidence": "patch-seq + morphology; community detection on probabilistic mapping (Gouwens 2020)",
  "effect_size": "5 Vip MET-types; Vip-MET-1 regular sustained, Vip-MET-2 irregular, Vip-MET-4/5 elevated sag",
  "text_access": "fulltext",
  "study_system": "mouse VISp; patch-seq",
  "_source_cluster": "cluster_04_intrinsic_electrophysiology",
  "replication_status": "novel",
  "_source_cluster_index": 63,
  "claim_source_sentence": "We identified five Vip met-types ( Figure 7I – L ), all resembling bipolar or bitufted cells.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Vip-MET-1 also typically had regular, sustained firing while Vip-MET-2 firing was usually irregular."
}
source_refs
[
  "paper:paper-pm-33186530"
]
evidence_refs
[
  {
    "ref": "paper:paper-pm-33186530"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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