Details

scope
Developing rodent brain, perineuronal net formation
claim_text
Perineuronal nets, which preferentially surround PV interneurons, are fundamental to postnatal experience-dependent maturation of inhibitory circuits and their disruption has implications for neurodevelopmental disorders.
section_id
section_13_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-13
source_kind
review_finding
source_path
evidence/section_13_evidence_package.json
source_span
Perineuronal nets in the developing brain: implications for neurodevelopmental disorders.
study_system
Developing rodent brain, perineuronal net formation
section_title
Cross-Cluster Synthesis: What Replicates, What Is Contested, What Is Untested
evidence_summary
Perineuronal nets, which preferentially surround PV interneurons, are fundamental to postnatal experience-dependent maturation of inhibitory circuits and their disruption has implications for neurodevelopmental disorders.
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-13
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1186/s13041-025-01261-3",
  "claim": "Perineuronal nets, which preferentially surround PV interneurons, are fundamental to postnatal experience-dependent maturation of inhibitory circuits and their disruption has implications for neurodevelopmental disorders.",
  "evidence": "Perineuronal nets, which preferentially surround PV interneurons, are fundamental to postnatal experience-dependent maturation of inhibitory circuits and their disruption has implications for neurodevelopmental disorders.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "Developing rodent brain, perineuronal net formation",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Perineuronal nets in the developing brain: implications for neurodevelopmental disorders.",
  "replication_evidence_dois": [
    "10.1016/j.schres.2024.07.023",
    "10.3389/fncir.2024.1519704"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-7c02b15359d1"
]
evidence_refs
[
  {
    "ref": "paper:paper-7c02b15359d1"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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