Details
- scope
- Rodent stress models and human postmortem brain tissue
- claim_text
- Stress-related changes in PV cells are only reported in a minority of rodent studies, with positive findings being region-, age-, sex-, and stress recency-dependent; translation to humans remains limited.
- section_id
- section_13_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
- effect_size
- Minority of studies report significant PV changes
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-13
- source_kind
- review_finding
- source_path
- evidence/section_13_evidence_package.json
- study_system
- Rodent stress models and human postmortem brain tissue
- section_title
- Cross-Cluster Synthesis: What Replicates, What Is Contested, What Is Untested
- evidence_summary
- Stress-related changes in PV cells are only reported in a minority of rodent studies, with positive findings being region-, age-, sex-, and stress recency-dependent; translation to humans remains limited.
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- contested
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-13
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
- raw_fields
{ "n": 0, "doi": "10.1016/j.ynstr.2021.100380", "claim": "Stress-related changes in PV cells are only reported in a minority of rodent studies, with positive findings being region-, age-, sex-, and stress recency-dependent; translation to humans remains limited.", "evidence": "Stress-related changes in PV cells are only reported in a minority of rodent studies, with positive findings being region-, age-, sex-, and stress recency-dependent; translation to humans remains limited.", "effect_size": "Minority of studies report significant PV changes", "text_access": "fulltext", "study_system": "Rodent stress models and human postmortem brain tissue", "replication_status": "contested", "claim_source_sentence": "Its principal findings, derived mainly from rodent studies, are that stress-related changes in PV cells are only reported in a minority of studies, that positive findings are region-, age-, sex-, and stress recency-dependent, and that antidepressants protect from stress-induced apparent PV cell loss.", "replication_evidence_dois": [ "10.3389/fphar.2021.689473" ], "effect_size_source_sentence": "Its principal findings, derived mainly from rodent studies, are that stress-related changes in PV cells are only reported in a minority of studies, that positive findings are region-, age-, sex-, and stress recency-dependent." }- source_refs
[ "paper:paper-f309f67acd4e" ]
- source_span
Its principal findings, derived mainly from rodent studies, are that stress-related changes in PV cells are only reported in a minority of studies, that positive findings are region-, age-, sex-, and stress recency-dependent, and that antidepressants protect from stress-induced apparent PV cell loss.
- evidence_refs
[ { "ref": "paper:paper-f309f67acd4e" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }