Details
- scope
- Rodent models of schizophrenia (pharmacological, neurodevelopmental, genetic)
- claim_text
- PV levels are significantly reduced in PFC and hippocampus across all categories of schizophrenia animal models, but pharmacological, neurodevelopmental, and genetic models show differential effects by brain region.
- section_id
- section_13_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
- effect_size
- Significant reduction across all model types
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-13
- source_kind
- review_finding
- source_path
- evidence/section_13_evidence_package.json
- source_span
- Our results confirmed that PV levels are significantly reduced in the PFC and HIP regardless of the animal model.
- study_system
- Rodent models of schizophrenia (pharmacological, neurodevelopmental, genetic)
- section_title
- Cross-Cluster Synthesis: What Replicates, What Is Contested, What Is Untested
- evidence_summary
- PV levels are significantly reduced in PFC and hippocampus across all categories of schizophrenia animal models, but pharmacological, neurodevelopmental, and genetic models show differential effects by brain region.
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-13
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1093/schbul/sbad123", "claim": "PV levels are significantly reduced in PFC and hippocampus across all categories of schizophrenia animal models, but pharmacological, neurodevelopmental, and genetic models show differential effects by brain region.", "evidence": "PV levels are significantly reduced in PFC and hippocampus across all categories of schizophrenia animal models, but pharmacological, neurodevelopmental, and genetic models show differential effects by brain region.", "effect_size": "Significant reduction across all model types", "text_access": "fulltext", "study_system": "Rodent models of schizophrenia (pharmacological, neurodevelopmental, genetic)", "replication_status": "independently_replicated", "claim_source_sentence": "Our results confirmed that PV levels are significantly reduced in the PFC and HIP regardless of the animal model.", "replication_evidence_dois": [ "10.1007/s00702-019-02080-2", "10.1016/j.neubiorev.2023.105488" ], "effect_size_source_sentence": "Our results confirmed that PV levels are significantly reduced in the PFC and HIP regardless of the animal model." }- source_refs
[ "paper:paper-24a9d21b34c0" ]
- evidence_refs
[ { "ref": "paper:paper-24a9d21b34c0" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }