Details

scope
Computational model of CA1 hippocampal pyramidal cells (40 morphologies)
claim_text
Separate feedforward inhibition by basket and bistratified interneurons modulates pyramidal cell threshold and gain respectively; concomitant FFI synergistically extends dynamic range of CA1 pyramidal cells.
section_id
section_13_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
effect_size
Synergistic extension of dynamic range
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-13
source_kind
review_finding
source_path
evidence/section_13_evidence_package.json
study_system
Computational model of CA1 hippocampal pyramidal cells (40 morphologies)
section_title
Cross-Cluster Synthesis: What Replicates, What Is Contested, What Is Untested
evidence_summary
Separate feedforward inhibition by basket and bistratified interneurons modulates pyramidal cell threshold and gain respectively; concomitant FFI synergistically extends dynamic range of CA1 pyramidal cells.
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-13
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": 40,
  "doi": "10.3389/fncel.2015.00439",
  "claim": "Separate feedforward inhibition by basket and bistratified interneurons modulates pyramidal cell threshold and gain respectively; concomitant FFI synergistically extends dynamic range of CA1 pyramidal cells.",
  "evidence": "Separate feedforward inhibition by basket and bistratified interneurons modulates pyramidal cell threshold and gain respectively; concomitant FFI synergistically extends dynamic range of CA1 pyramidal cells.",
  "effect_size": "Synergistic extension of dynamic range",
  "text_access": "fulltext",
  "study_system": "Computational model of CA1 hippocampal pyramidal cells (40 morphologies)",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Separate FFI by basket and bistratified respectively modulated CA1PC threshold and gain. Concomitant FFI by both interneuron types synergistically extended the dynamic range of CA1PCs by buffering their spiking response to excitatory stimulation.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Concomitant FFI by both interneuron types synergistically extended the dynamic range of CA1PCs by buffering their spiking response to excitatory stimulation."
}
source_refs
[
  "paper:paper-15ebb7f64a09"
]
source_span
Separate FFI by basket and bistratified respectively modulated CA1PC threshold and gain. Concomitant FFI by both interneuron types synergistically extended the dynamic range of CA1PCs by buffering their spiking response to excitatory stimulation.
evidence_refs
[
  {
    "ref": "paper:paper-15ebb7f64a09"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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