Meta-analyses of brain and blood samples reveal altered expression of GABA-rela…

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scope: Human brain, blood, iPSC organoids; meta-analysis
claim_text: Meta-analyses of brain and blood samples reveal altered expression of GABA-related genes in schizophrenia including GAD67 and parvalbumin, with iPSC-derived organoids providing convergent evidence.
section_id: section_13_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-13
source_kind: review_finding
source_path: evidence/section_13_evidence_package.json
source_span: Altered Expression of GABA-Related Genes in Schizophrenia: Insights from Meta-Analyses of Brain and Blood Samples and iPSC-Derived Organoids.
study_system: Human brain, blood, iPSC organoids; meta-analysis
section_title: Cross-Cluster Synthesis: What Replicates, What Is Contested, What Is Untested
evidence_summary: Meta-analyses of brain and blood samples reveal altered expression of GABA-related genes in schizophrenia including GAD67 and parvalbumin, with iPSC-derived organoids providing convergent evidence.
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: independently_replicated
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-13
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.31083/AP43531",
  "claim": "Meta-analyses of brain and blood samples reveal altered expression of GABA-related genes in schizophrenia including GAD67 and parvalbumin, with iPSC-derived organoids providing convergent evidence.",
  "evidence": "Meta-analyses of brain and blood samples reveal altered expression of GABA-related genes in schizophrenia including GAD67 and parvalbumin, with iPSC-derived organoids providing convergent evidence.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "Human brain, blood, iPSC organoids; meta-analysis",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Altered Expression of GABA-Related Genes in Schizophrenia: Insights from Meta-Analyses of Brain and Blood Samples and iPSC-Derived Organoids.",
  "replication_evidence_dois": [
    "10.1007/s00702-019-02080-2",
    "10.1093/schbul/sbad123"
  ],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-de69a1db5c29"
]

evidence_refs

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  }
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source_policy

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Meta-analyses of brain and blood samples reveal altered expression of GABA-rela…

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