Details

scope
mouse visual cortex GABAergic interneurons
claim_text
Cortical GABAergic interneurons can be classified into 28 multimodal met-types with congruent morphological, electrophysiological, and transcriptomic properties, with Pvalb types showing both discrete and continuous variation among t-types.
section_id
section_05_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_05_evidence_package.json
effect_size
28 met-types from >4,200 transcriptomes and 517 morphologies
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-05
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
Through multimodal integrated analysis we define 28 met-types that have congruent morphological, electrophysiological, and transcriptomic properties and robust mutual predictability.
study_system
mouse visual cortex GABAergic interneurons
section_title
Intrinsic Electrophysiology: The Fast-Spiking Phenotype and Its Variants
evidence_summary
Characterized >4,200 mouse visual cortical GABAergic interneurons with Patch-seq and reconstructed morphologies of 517 neurons. Most t-types have consistent electrophysiological and morphological properties.
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-05
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_05_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
raw_fields
{
  "n": 4200,
  "doi": "10.1016/j.cell.2020.09.057",
  "claim": "Cortical GABAergic interneurons can be classified into 28 multimodal met-types with congruent morphological, electrophysiological, and transcriptomic properties, with Pvalb types showing both discrete and continuous variation among t-types.",
  "evidence": "Characterized >4,200 mouse visual cortical GABAergic interneurons with Patch-seq and reconstructed morphologies of 517 neurons. Most t-types have consistent electrophysiological and morphological properties.",
  "effect_size": "28 met-types from >4,200 transcriptomes and 517 morphologies",
  "text_access": "fulltext",
  "study_system": "mouse visual cortex GABAergic interneurons",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Through multimodal integrated analysis we define 28 met-types that have congruent morphological, electrophysiological, and transcriptomic properties and robust mutual predictability.",
  "replication_evidence_dois": [
    "10.1126/science.adf6484"
  ],
  "effect_size_source_sentence": "we characterized the transcriptomes and intrinsic physiological properties of over 4,200 mouse visual cortical GABAergic interneurons and reconstructed the local morphologies of 517 of those neurons."
}
source_refs
[
  "paper:paper-pm-33186530"
]
evidence_refs
[
  {
    "ref": "paper:paper-pm-33186530"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.