Details

scope
Mouse, marmoset, and human primary motor cortex; multimodal molecular and spatial cell-type profiling
claim_text
Cross-species analysis achieves a consensus taxonomy of cortical transcriptomic types whose hierarchical organization is conserved from mouse to marmoset and human in primary motor cortex.
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-12
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
source_span
Second, cross-species analysis achieves a consensus taxonomy of transcriptomic types and their hierarchical organization that is conserved from mouse to marmoset and human.
study_system
Mouse, marmoset, and human primary motor cortex; multimodal molecular and spatial cell-type profiling
section_title
Whole-Brain Connectomics: Mouse, Primate, Human
evidence_summary
Multimodal cell census integrates transcriptome, open chromatin, and DNA methylation; in situ single-cell transcriptomics provides a spatially resolved cell-type atlas of motor cortex.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-12
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1038/s41586-021-03950-0",
  "claim": "Cross-species analysis achieves a consensus taxonomy of cortical transcriptomic types whose hierarchical organization is conserved from mouse to marmoset and human in primary motor cortex.",
  "cite_key": "Callaway2021",
  "evidence": "Multimodal cell census integrates transcriptome, open chromatin, and DNA methylation; in situ single-cell transcriptomics provides a spatially resolved cell-type atlas of motor cortex.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "Mouse, marmoset, and human primary motor cortex; multimodal molecular and spatial cell-type profiling",
  "source_cluster_id": "cluster_11",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Second, cross-species analysis achieves a consensus taxonomy of transcriptomic types and their hierarchical organization that is conserved from mouse to marmoset and human.",
  "replication_evidence_dois": [
    "10.1371/journal.pbio.3002133",
    "10.1038/s41586-021-03970-w"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-pm-34616075"
]
evidence_refs
[
  {
    "ref": "paper:paper-pm-34616075"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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