The caudal ganglionic eminence (CGE) is the developmental origin of all VIP-exp…

{
  "n": null,
  "doi": "10.1002/dneu.20853",
  "claim": "The caudal ganglionic eminence (CGE) is the developmental origin of all VIP-expressing cortical interneurons and at least 90% of 5HT3aR-expressing cortical interneurons.",
  "title": null,
  "cite_key": "Rudy2011",
  "evidence": "Genetic fate mapping with 5HT3a-Cre/Htr3a-BACEGFP and CGE region-specific markers in mouse embryos; nine electrophysiological subtypes characterized at adulthood, six accounting for >93% of CGE-derived population.",
  "effect_size": "≥90% of 5HT3aR cortical interneurons CGE-derived; 100% of VIP cortical interneurons CGE-derived",
  "figure_data": [
    {
      "type": "lineage_fraction",
      "unit": "percent (≥)",
      "value": 90,
      "metric": "% cortical 5HT3aR interneurons originating in CGE",
      "source": "Lee/Rudy 2011 review (citing Miyoshi 2010)",
      "context": "remaining ~10% from MGE/preoptic area"
    },
    {
      "type": "lineage_fraction",
      "unit": "percent",
      "value": 100,
      "metric": "% cortical VIP interneurons originating in CGE",
      "source": "Lee/Rudy 2011 review (citing Miyoshi 2010)",
      "context": ""
    }
  ],
  "text_access": "fulltext",
  "study_system": "mouse, CGE-derived cortical interneurons (review citing Miyoshi 2010)",
  "_source_cluster": "cluster_02_development_lineage",
  "replication_status": "review",
  "_source_cluster_index": 85,
  "claim_source_sentence": "In their characterization of the interneurons that originate in the caudal ganglionic eminence (CGE), where all VIP and at least 90% of 5HT3aR neurons originate (see below), Myoshi et al. (2010) described nine electrophysiologically different subtypes, of which six accounted for >93% of the CGE population.",
  "replication_evidence_dois": [
    "10.1523/jneurosci.1869-10.2010"
  ],
  "effect_size_source_sentence": "In their characterization of the interneurons that originate in the caudal ganglionic eminence (CGE), where all VIP and at least 90% of 5HT3aR neurons originate (see below), Myoshi et al. (2010) described nine electrophysiologically different subtypes, of which six accounted for >93% of the CGE population."
}

[
  "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
]

In their characterization of the interneurons that originate in the caudal ganglionic eminence (CGE), where all VIP and at least 90% of 5HT3aR neurons originate (see below), Myoshi et al. (2010) described nine electrophysiologically different subtypes, of which six accounted for >93% of the CGE population.

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  "notes": [
    "Local review repositories are read-only inputs.",
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  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
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