Details

scope
mouse cortex (review/synthesis of multiple studies)
section_id
section_03
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
effect_size
VIP IS2 / rapid-adapting subtype is the major VIP+/CR- type
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-03-development
source_kind
review_finding
source_path
evidence/section_03_evidence_package.json
source_span
These cells have been named rapid-adapting ( Butt et al., 2005 ), fast-adapting ( Lee et al., 2010 ; Miyoshi et al., 2010 ), and IS2 ( Porter et al., 1998 ) and seem to be the major VIP subtype that does not coexpress CR.
study_system
mouse cortex (review/synthesis of multiple studies)
section_title
Developmental Origins and Postnatal Maturation
evidence_summary
Cross-referenced electrophysiological characterization studies (Butt 2005; Lee 2010; Miyoshi 2010; Porter 1998) plus VIP/CR co-expression analysis.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
review
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-03-development
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
Within the cortical VIP+ interneuron population, a major non-calretinin-coexpressing subtype is the rapid-adapting / fast-adapting / IS2 cell, which targets other interneurons (interneuron-selective IS2 functional class) and is electrophysiologically distinct from the VIP+/CR+ bipolar IS3-type population.
raw_fields
{
  "n": null,
  "doi": "10.1002/dneu.20853",
  "claim": "Within the cortical VIP+ interneuron population, a major non-calretinin-coexpressing subtype is the rapid-adapting / fast-adapting / IS2 cell, which targets other interneurons (interneuron-selective IS2 functional class) and is electrophysiologically distinct from the VIP+/CR+ bipolar IS3-type population.",
  "title": null,
  "cite_key": "Rudy2011",
  "evidence": "Cross-referenced electrophysiological characterization studies (Butt 2005; Lee 2010; Miyoshi 2010; Porter 1998) plus VIP/CR co-expression analysis.",
  "effect_size": "VIP IS2 / rapid-adapting subtype is the major VIP+/CR- type",
  "figure_data": [],
  "text_access": "fulltext",
  "study_system": "mouse cortex (review/synthesis of multiple studies)",
  "_source_cluster": "cluster_02_development_lineage",
  "replication_status": "review",
  "_source_cluster_index": 112,
  "claim_source_sentence": "These cells have been named rapid-adapting ( Butt et al., 2005 ), fast-adapting ( Lee et al., 2010 ; Miyoshi et al., 2010 ), and IS2 ( Porter et al., 1998 ) and seem to be the major VIP subtype that does not coexpress CR.",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2005.09.034",
    "10.1523/jneurosci.1869-10.2010"
  ],
  "effect_size_source_sentence": "These cells have been named rapid-adapting ( Butt et al., 2005 ), fast-adapting ( Lee et al., 2010 ; Miyoshi et al., 2010 ), and IS2 ( Porter et al., 1998 ) and seem to be the major VIP subtype that does not coexpress CR."
}
source_refs
[
  "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
]
evidence_refs
[
  {
    "ref": "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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