Details
- scope
- mouse, primary somatosensory cortex (layer I)
- claim_text
- Almost all GABAergic interneurons in cortical layer I (which contains only inhibitory neurons, no excitatory cells) express 5HT3aR, indicating that layer I interneurons are predominantly CGE-derived.
- section_id
- section_03
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
- effect_size
- ≈100% of layer I GABAergic interneurons are 5HT3aR-positive
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-03-development
- source_kind
- review_finding
- source_path
- evidence/section_03_evidence_package.json
- source_span
- Almost all neurons in layer I, a layer that only contains GABAergic interneurons, are 5HT3aR-expressing.
- study_system
- mouse, primary somatosensory cortex (layer I)
- section_title
- Developmental Origins and Postnatal Maturation
- evidence_summary
- Double in situ hybridization (GAD67 + 5HT3aR/PV/SST) on mouse primary somatosensory cortex; quantitative laminar distribution.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- review
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-03-development
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1002/dneu.20853", "claim": "Almost all GABAergic interneurons in cortical layer I (which contains only inhibitory neurons, no excitatory cells) express 5HT3aR, indicating that layer I interneurons are predominantly CGE-derived.", "title": null, "cite_key": "Rudy2011", "evidence": "Double in situ hybridization (GAD67 + 5HT3aR/PV/SST) on mouse primary somatosensory cortex; quantitative laminar distribution.", "effect_size": "≈100% of layer I GABAergic interneurons are 5HT3aR-positive", "figure_data": [ { "type": "lineage_fraction", "unit": "percent (≈)", "value": 100, "metric": "% layer I GABAergic interneurons expressing 5HT3aR", "source": "Lee/Rudy 2011 review", "context": "layer I contains only GABAergic interneurons in cortex" } ], "text_access": "fulltext", "study_system": "mouse, primary somatosensory cortex (layer I)", "_source_cluster": "cluster_02_development_lineage", "replication_status": "review", "_source_cluster_index": 88, "claim_source_sentence": "Almost all neurons in layer I, a layer that only contains GABAergic interneurons, are 5HT3aR-expressing.", "replication_evidence_dois": [ "10.1002/dneu.20853" ], "effect_size_source_sentence": "Almost all neurons in layer I, a layer that only contains GABAergic interneurons, are 5HT3aR-expressing." }- source_refs
[ "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9" ]
- evidence_refs
[ { "ref": "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }