Details

scope
mouse, primary somatosensory cortex (layer I)
claim_text
Almost all GABAergic interneurons in cortical layer I (which contains only inhibitory neurons, no excitatory cells) express 5HT3aR, indicating that layer I interneurons are predominantly CGE-derived.
section_id
section_03
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
effect_size
≈100% of layer I GABAergic interneurons are 5HT3aR-positive
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-03-development
source_kind
review_finding
source_path
evidence/section_03_evidence_package.json
source_span
Almost all neurons in layer I, a layer that only contains GABAergic interneurons, are 5HT3aR-expressing.
study_system
mouse, primary somatosensory cortex (layer I)
section_title
Developmental Origins and Postnatal Maturation
evidence_summary
Double in situ hybridization (GAD67 + 5HT3aR/PV/SST) on mouse primary somatosensory cortex; quantitative laminar distribution.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
review
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-03-development
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1002/dneu.20853",
  "claim": "Almost all GABAergic interneurons in cortical layer I (which contains only inhibitory neurons, no excitatory cells) express 5HT3aR, indicating that layer I interneurons are predominantly CGE-derived.",
  "title": null,
  "cite_key": "Rudy2011",
  "evidence": "Double in situ hybridization (GAD67 + 5HT3aR/PV/SST) on mouse primary somatosensory cortex; quantitative laminar distribution.",
  "effect_size": "≈100% of layer I GABAergic interneurons are 5HT3aR-positive",
  "figure_data": [
    {
      "type": "lineage_fraction",
      "unit": "percent (≈)",
      "value": 100,
      "metric": "% layer I GABAergic interneurons expressing 5HT3aR",
      "source": "Lee/Rudy 2011 review",
      "context": "layer I contains only GABAergic interneurons in cortex"
    }
  ],
  "text_access": "fulltext",
  "study_system": "mouse, primary somatosensory cortex (layer I)",
  "_source_cluster": "cluster_02_development_lineage",
  "replication_status": "review",
  "_source_cluster_index": 88,
  "claim_source_sentence": "Almost all neurons in layer I, a layer that only contains GABAergic interneurons, are 5HT3aR-expressing.",
  "replication_evidence_dois": [
    "10.1002/dneu.20853"
  ],
  "effect_size_source_sentence": "Almost all neurons in layer I, a layer that only contains GABAergic interneurons, are 5HT3aR-expressing."
}
source_refs
[
  "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
]
evidence_refs
[
  {
    "ref": "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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