- claim_text
Multi-modal spatial, transcriptomic, and epigenomic analyses reveal that PV neurons in the spinal dorsal horn have distinct molecular programs compared to cortical PV interneurons, challenging assumptions of uniform PV identity across brain regions.
- raw_fields
{
"n": 0,
"doi": "10.1016/j.celrep.2024.114876",
"claim": "Multi-modal spatial, transcriptomic, and epigenomic analyses reveal that PV neurons in the spinal dorsal horn have distinct molecular programs compared to cortical PV interneurons, challenging assumptions of uniform PV identity across brain regions.",
"evidence": "Multi-modal spatial, transcriptomic, and epigenomic analyses reveal that PV neurons in the spinal dorsal horn have distinct molecular programs compared to cortical PV interneurons, challenging assumptions of uniform PV identity across brain regions.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "Mouse spinal dorsal horn, multi-omics",
"replication_status": "replication_unknown",
"claim_source_sentence": "Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-a1f7dbd2c836"
]
- evidence_refs
[
{
"ref": "paper:paper-a1f7dbd2c836"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}- evidence_summary
Multi-modal spatial, transcriptomic, and epigenomic analyses reveal that PV neurons in the spinal dorsal horn have distinct molecular programs compared to cortical PV interneurons, challenging assumptions of uniform PV identity across brain regions.