Mouse auditory cortex layer 6 Ntsr1-Cre+ corticothalamic neurons begin spiking…

{
  "n": null,
  "doi": "10.1016/j.cub.2020.10.027",
  "claim": "Mouse auditory cortex layer 6 Ntsr1-Cre+ corticothalamic neurons begin spiking hundreds of milliseconds before orofacial movements linked to sound and reward — but not before unrelated movements such as locomotion.",
  "cite_key": "Clayton2021",
  "evidence": "Optogenetically targeted single-unit recordings and two-photon imaging of Ntsr1-Cre+ L6 CT neurons in primary auditory cortex during an active-listening task.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse primary auditory cortex (A1) layer 6, Ntsr1-Cre line, awake behaving",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We found that L6 CTs and other L6 units began spiking hundreds of milliseconds prior to orofacial movements linked to sound presentation and reward, but not to other movements such as locomotion, which were not linked to an explicit behavioral task.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

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]

We found that L6 CTs and other L6 units began spiking hundreds of milliseconds prior to orofacial movements linked to sound presentation and reward, but not to other movements such as locomotion, which were not linked to an explicit behavioral task.

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