- claim_text
A whole-isocortex single-cell transcriptomic atlas of ~1.3 million cells defines a taxonomy of glutamatergic and GABAergic neuron types across the adult mouse isocortex and hippocampal formation, with large-scale continuous and graded variations of cell types along isocortical depth and across the cortical sheet.
- raw_fields
{
"n": "~1.3 million cells profiled",
"doi": "10.1016/j.cell.2021.04.021",
"claim": "A whole-isocortex single-cell transcriptomic atlas of ~1.3 million cells defines a taxonomy of glutamatergic and GABAergic neuron types across the adult mouse isocortex and hippocampal formation, with large-scale continuous and graded variations of cell types along isocortical depth and across the cortical sheet.",
"cite_key": "Yao2021a",
"evidence": "Droplet-based single-cell RNA-seq of ~1.3 million adult mouse cells covering the entire isocortex and hippocampal formation.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "mouse isocortex and hippocampal formation, single-cell RNA-seq taxonomy",
"argument_role": "supporting",
"replication_status": "replication_unknown",
"claim_source_sentence": "We profiled ∼1.3 million cells covering the entire adult mouse isocortex and HPF and derived a transcriptomic cell-type taxonomy revealing a comprehensive repertoire of glutamatergic and GABAergic neuron types... We also identify large-scale continuous and graded variations of cell types along isocortical depth, across the isocortical sheet, and in multiple dimensions in hippocampus and subiculum.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-4dfe44516146"
]
- source_span
We profiled ∼1.3 million cells covering the entire adult mouse isocortex and HPF and derived a transcriptomic cell-type taxonomy revealing a comprehensive repertoire of glutamatergic and GABAergic neuron types... We also identify large-scale continuous and graded variations of cell types along isocortical depth, across the isocortical sheet, and in multiple dimensions in hippocampus and subiculum.
- evidence_refs
[
{
"ref": "paper:paper-4dfe44516146"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}