Details

scope
mouse somatosensory cortex (S1) layer 5, in vivo, all-optical
claim_text
All-optical input-output mapping in mouse S1 layer 5 in vivo shows horizontal propagation of excitation is limited to ~130 µm from the photostimulation center, supporting a functional column-like architecture within L5.
section_id
section_01
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
effect_size
λ < 130 µm
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-01-introduction
source_kind
review_finding
source_path
evidence/section_01_evidence_package.json
source_span
The excitability was spread around the blue-light irradiated region, but the horizontal propagation was limited to within a certain distance (λ < 130 μm from the center of the illumination spot).
study_system
mouse somatosensory cortex (S1) layer 5, in vivo, all-optical
section_title
1. Introduction — what "excitatory recurrence" means operationally in mouse cortex, and why isolating it from inhibition and from clinical framings is a defensible analytic move for basic-research synthesis
evidence_summary
In vivo two-photon imaging of R-CaMP2 combined with focal blue-light optogenetic excitation through a microprism in mouse somatosensory cortex.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-01-introduction
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1007/s12576-018-0618-4",
  "claim": "All-optical input-output mapping in mouse S1 layer 5 in vivo shows horizontal propagation of excitation is limited to ~130 µm from the photostimulation center, supporting a functional column-like architecture within L5.",
  "cite_key": "Koizumi2019",
  "evidence": "In vivo two-photon imaging of R-CaMP2 combined with focal blue-light optogenetic excitation through a microprism in mouse somatosensory cortex.",
  "effect_size": "λ < 130 µm",
  "text_access": "abstract_only",
  "study_system": "mouse somatosensory cortex (S1) layer 5, in vivo, all-optical",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "The excitability was spread around the blue-light irradiated region, but the horizontal propagation was limited to within a certain distance (λ < 130 μm from the center of the illumination spot).",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "The excitability was spread around the blue-light irradiated region, but the horizontal propagation was limited to within a certain distance (λ < 130 μm from the center of the illumination spot)."
}
source_refs
[
  "paper:paper-69ca04b2410c"
]
evidence_refs
[
  {
    "ref": "paper:paper-69ca04b2410c"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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