- raw_fields
{
"n": 0,
"doi": "10.1073/pnas.0813176106",
"claim": "Hippocampal theta rhythm and theta-gamma coupling require fast inhibition onto PV-positive interneurons, but gamma oscillations persist without it",
"evidence": "Genetic ablation of synaptic inhibition in PV+ interneurons (PV-Δγ2 mice) combined with computational network model",
"effect_size": "theta rhythm strongly reduced; gamma oscillations not altered",
"text_access": "fulltext",
"study_system": "PV-Δγ2 transgenic mice, hippocampal CA1, computational model",
"replication_status": "replication_unknown",
"claim_source_sentence": "Hippocampal local field potential and unit recordings in the CA1 area of freely behaving mice revealed that theta rhythm was strongly reduced in these mice. The characteristic coupling of theta and gamma oscillations was strongly altered in PV-Δγ2 mice more than could be accounted for by the reduction in theta rhythm only. Surprisingly, gamma oscillations were not altered.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "Hippocampal local field potential and unit recordings in the CA1 area of freely behaving mice revealed that theta rhythm was strongly reduced in these mice."
}- source_refs
[
"paper:paper-5b5d1f4b5090"
]
- source_span
Hippocampal local field potential and unit recordings in the CA1 area of freely behaving mice revealed that theta rhythm was strongly reduced in these mice. The characteristic coupling of theta and gamma oscillations was strongly altered in PV-Δγ2 mice more than could be accounted for by the reduction in theta rhythm only. Surprisingly, gamma oscillations were not altered.
- evidence_refs
[
{
"ref": "paper:paper-5b5d1f4b5090"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}