Details
- scope
- computational network model, mouse medial entorhinal cortex brain slices
- claim_text
- Fast-spiking interneurons autonomously generate fast gamma oscillations via ING mechanism, with excitation strength tuning ING-PING transitions
- section_id
- section_12_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_12_evidence_package.json
- effect_size
- ING: ~100-140 Hz; PING: 60-100 Hz
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-12
- source_kind
- review_finding
- source_path
- evidence/section_12_evidence_package.json
- source_span
- Simulations revealed that weak excitatory input to interneurons supports fast ING-dominated rhythms (∼100–140 Hz) while strengthening excitatory drive induces a transition to slower PING-dominated oscillations (60–100 Hz).
- study_system
- computational network model, mouse medial entorhinal cortex brain slices
- section_title
- Computational Models of PV Circuit Function
- evidence_summary
- Optogenetic stimulation and computational network models constrained by experimental data from mouse mEC
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-12
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_12_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1523/ENEURO.0452-25.2026", "claim": "Fast-spiking interneurons autonomously generate fast gamma oscillations via ING mechanism, with excitation strength tuning ING-PING transitions", "evidence": "Optogenetic stimulation and computational network models constrained by experimental data from mouse mEC", "effect_size": "ING: ~100-140 Hz; PING: 60-100 Hz", "text_access": "fulltext", "study_system": "computational network model, mouse medial entorhinal cortex brain slices", "replication_status": "replication_unknown", "claim_source_sentence": "Simulations revealed that weak excitatory input to interneurons supports fast ING-dominated rhythms (∼100–140 Hz) while strengthening excitatory drive induces a transition to slower PING-dominated oscillations (60–100 Hz).", "replication_evidence_dois": [], "effect_size_source_sentence": "Simulations revealed that weak excitatory input to interneurons supports fast ING-dominated rhythms (∼100–140 Hz) while strengthening excitatory drive induces a transition to slower PING-dominated oscillations (60–100 Hz)." }- source_refs
[ "paper:paper-ba61b70940a1" ]
- evidence_refs
[ { "ref": "paper:paper-ba61b70940a1" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }