Details

scope
mouse somatosensory cortex; PV-Cre, SST-Cre, VIP-Cre
section_id
section_11
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-11
source_kind
review_finding
source_path
evidence/section_11_evidence_package.json
source_span
Cortical and thalamic inputs were greatest onto VIP+ interneurons and smallest onto SST+ neurons.
study_system
mouse somatosensory cortex; PV-Cre, SST-Cre, VIP-Cre
section_title
Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)
evidence_summary
EnvA-G-deleted rabies + PV-Cre/SST-Cre/VIP-Cre starter cells in mouse somatosensory cortex.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-11
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
claim_text
Monosynaptic rabies tracing in PV-Cre, SST-Cre, and VIP-Cre mice reveals that VIP+ interneurons receive more long-range cortical and thalamic input than SST+ neurons (with PV+ intermediate), with VIP+ inputs preferentially from deep layers and SST+ inputs from superficial layers — supporting a brain-wide circuit motif for VIP-mediated cortical disinhibition.
raw_fields
{
  "n": 0,
  "doi": "10.1523/jneurosci.3967-15.2016",
  "claim": "Monosynaptic rabies tracing in PV-Cre, SST-Cre, and VIP-Cre mice reveals that VIP+ interneurons receive more long-range cortical and thalamic input than SST+ neurons (with PV+ intermediate), with VIP+ inputs preferentially from deep layers and SST+ inputs from superficial layers — supporting a brain-wide circuit motif for VIP-mediated cortical disinhibition.",
  "cite_key": "Wall2016",
  "evidence": "EnvA-G-deleted rabies + PV-Cre/SST-Cre/VIP-Cre starter cells in mouse somatosensory cortex.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse somatosensory cortex; PV-Cre, SST-Cre, VIP-Cre",
  "source_cluster_id": "cluster_10",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Cortical and thalamic inputs were greatest onto VIP+ interneurons and smallest onto SST+ neurons.",
  "replication_evidence_dois": [
    "10.1038/s41593-018-0322-y",
    "10.1016/j.celrep.2019.08.064"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-32a4e1ae2010"
]
evidence_refs
[
  {
    "ref": "paper:paper-32a4e1ae2010"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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