Monosynaptic rabies tracing demonstrates that sensory cortical and limbic struc…

Details

scope: mouse, dorsomedial striatum
claim_text: Monosynaptic rabies tracing demonstrates that sensory cortical and limbic structures preferentially innervate the direct (D1) striatal pathway whereas motor cortex preferentially targets the indirect (D2) pathway.
section_id: section_11
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
review_repo: ComputationalReviewLoops
section_ref: wiki_page:computationalreviewloops-11
source_kind: review_finding
source_path: evidence/section_11_evidence_package.json
source_span: We discovered that sensory cortical and limbic structures preferentially innervated the direct pathway, whereas motor cortex preferentially targeted the indirect pathway.
study_system: mouse, dorsomedial striatum
section_title: Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)
evidence_summary: Cre-dependent G-deleted rabies tracing in D1-Cre and D2-Cre mice with brain-wide quantification.
review_bundle_ref: analysis_bundle:ab-d49e54403ef9
replication_status: contested
review_package_ref: analysis_bundle:ab-d49e54403ef9
source_artifact_ref: wiki_page:computationalreviewloops-11
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
commit_sha: 0632aae8abc141909207fe91f6349b9e36489c3b
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1016/j.neuron.2013.05.014",
  "claim": "Monosynaptic rabies tracing demonstrates that sensory cortical and limbic structures preferentially innervate the direct (D1) striatal pathway whereas motor cortex preferentially targets the indirect (D2) pathway.",
  "cite_key": "Wall2013",
  "evidence": "Cre-dependent G-deleted rabies tracing in D1-Cre and D2-Cre mice with brain-wide quantification.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse, dorsomedial striatum",
  "source_cluster_id": "cluster_10",
  "replication_status": "contested",
  "claim_source_sentence": "We discovered that sensory cortical and limbic structures preferentially innervated the direct pathway, whereas motor cortex preferentially targeted the indirect pathway.",
  "replication_evidence_dois": [
    "10.1371/journal.pone.0123381",
    "10.7554/elife.92992"
  ],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-f473954cf20b"
]

evidence_refs

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source_policy

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Monosynaptic rabies tracing demonstrates that sensory cortical and limbic struc…

Details

Replication

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