Details

scope
human + marmoset + mouse M1/MOp; snRNA-seq + snmC-seq2 + snATAC-seq
claim_text
Bakken et al. (2021) showed that more Vip subtype consensus clusters could be resolved by pairwise alignment between human and marmoset M1 than between either primate and mouse, indicating closer homology of VIP types within primates.
section_id
section_02
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-02-classification
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
source_span
More consensus clusters could be resolved by pairwise alignment between humans and marmosets than between either of these primates and mice, particularly for Vip subtypes.
study_system
human + marmoset + mouse M1/MOp; snRNA-seq + snmC-seq2 + snATAC-seq
section_title
Molecular Identity and Transcriptomic Taxonomy
evidence_summary
Cross-species integrative clustering of MOp/M1 across human, marmoset, mouse: Vip_2 consensus type splits into multiple homologous primate types, indicating greater intra-primate VIP diversity than primate-rodent.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-02-classification
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1038/s41586-021-03465-8",
  "claim": "Bakken et al. (2021) showed that more Vip subtype consensus clusters could be resolved by pairwise alignment between human and marmoset M1 than between either primate and mouse, indicating closer homology of VIP types within primates.",
  "title": null,
  "cite_key": "Bakken2021a",
  "evidence": "Cross-species integrative clustering of MOp/M1 across human, marmoset, mouse: Vip_2 consensus type splits into multiple homologous primate types, indicating greater intra-primate VIP diversity than primate-rodent.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "human + marmoset + mouse M1/MOp; snRNA-seq + snmC-seq2 + snATAC-seq",
  "target_section": "section_02",
  "_source_cluster": "cluster_01_molecular_taxonomy",
  "replication_status": "replicated",
  "_source_cluster_index": 12,
  "claim_source_sentence": "More consensus clusters could be resolved by pairwise alignment between humans and marmosets than between either of these primates and mice, particularly for Vip subtypes."
}
source_refs
[
  "paper:paper-pm-34616062"
]
evidence_refs
[
  {
    "ref": "paper:paper-pm-34616062"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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