Details
- scope
- mouse VISp + ALM; SMART-seq v4 scRNA-seq
- claim_text
- Tasic et al. (2018) defined six GABAergic subclasses (Sst, Pvalb, Vip, Lamp5, Sncg, Serpinf1) plus distinct Sst-Chodl and Meis2-Adamts19 types, with the major division reflecting MGE versus CGE developmental origin.
- section_id
- section_02
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-02-classification
- source_kind
- review_finding
- source_path
- evidence/section_02_evidence_package.json
- study_system
- mouse VISp + ALM; SMART-seq v4 scRNA-seq
- section_title
- Molecular Identity and Transcriptomic Taxonomy
- evidence_summary
- scRNA-seq of 23,822 cells from VISp and ALM yielded a hierarchical taxonomy with these six GABAergic subclasses; CGE-derived (Lamp5/Vip/Sncg/Serpinf1) form interconnected neighborhoods in the constellation diagram.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-02-classification
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- raw_fields
{ "n": 23822, "doi": "10.1038/s41586-018-0654-5", "claim": "Tasic et al. (2018) defined six GABAergic subclasses (Sst, Pvalb, Vip, Lamp5, Sncg, Serpinf1) plus distinct Sst-Chodl and Meis2-Adamts19 types, with the major division reflecting MGE versus CGE developmental origin.", "title": null, "cite_key": "Tasic2018", "evidence": "scRNA-seq of 23,822 cells from VISp and ALM yielded a hierarchical taxonomy with these six GABAergic subclasses; CGE-derived (Lamp5/Vip/Sncg/Serpinf1) form interconnected neighborhoods in the constellation diagram.", "effect_size": null, "text_access": "fulltext", "study_system": "mouse VISp + ALM; SMART-seq v4 scRNA-seq", "target_section": "section_02", "_source_cluster": "cluster_01_molecular_taxonomy", "replication_status": "replicated", "_source_cluster_index": 3, "claim_source_sentence": "We define six subclasses of GABAergic cells: Sst, Pvalb, Vip, Lamp5, Sncg and Serpinf1, and two distinct types: Sst-Chodl and Meis2-Adamts19. The major division among GABAergic types largely corresponds to their developmental origin in the medial ganglionic eminence (Pvalb and Sst subclasses) or caudal ganglionic eminence (Lamp5, Sncg, Serpinfl and Vip subclasses)." }- source_refs
[ "paper:paper-pm-30382198" ]
- source_span
We define six subclasses of GABAergic cells: Sst, Pvalb, Vip, Lamp5, Sncg and Serpinf1, and two distinct types: Sst-Chodl and Meis2-Adamts19. The major division among GABAergic types largely corresponds to their developmental origin in the medial ganglionic eminence (Pvalb and Sst subclasses) or caudal ganglionic eminence (Lamp5, Sncg, Serpinfl and Vip subclasses).
- evidence_refs
[ { "ref": "paper:paper-pm-30382198" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }