Details

scope
mouse PPC; behavior + opto + 2P imaging
section_id
section_02
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-02-classification
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
source_span
Disinhibition by VIP interneurons is orthogonal to cross-modal attentional modulation in posterior parietal cortex.
study_system
mouse PPC; behavior + opto + 2P imaging
section_title
Molecular Identity and Transcriptomic Taxonomy
evidence_summary
Two-photon calcium imaging + cell-type-specific opto manipulation of VIP cells in mouse PPC during cross-modal attention task.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-02-classification
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
VIP-mediated disinhibition of pyramidal cells in mouse PPC operates orthogonally to (i.e. is dissociable from) cross-modal attentional modulation: activating or inactivating VIP interneurons does not abolish attention-related response gain, indicating that VIP-driven disinhibition contributes a separable computational primitive rather than directly mediating attention.
raw_fields
{
  "n": null,
  "doi": "10.1016/j.neuron.2023.11.006",
  "claim": "VIP-mediated disinhibition of pyramidal cells in mouse PPC operates orthogonally to (i.e. is dissociable from) cross-modal attentional modulation: activating or inactivating VIP interneurons does not abolish attention-related response gain, indicating that VIP-driven disinhibition contributes a separable computational primitive rather than directly mediating attention.",
  "title": null,
  "cite_key": "Myersjoseph2024",
  "evidence": "Two-photon calcium imaging + cell-type-specific opto manipulation of VIP cells in mouse PPC during cross-modal attention task.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse PPC; behavior + opto + 2P imaging",
  "target_section": "section_05",
  "_source_cluster": "cluster_01_molecular_taxonomy",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 114,
  "claim_source_sentence": "Disinhibition by VIP interneurons is orthogonal to cross-modal attentional modulation in posterior parietal cortex.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-bcc613ccccd9"
]
evidence_refs
[
  {
    "ref": "paper:paper-bcc613ccccd9"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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