- claim_text
Long-range cingulate→V1 projections act through local GABAergic circuits to produce spatially structured top-down modulation: VIP interneurons are crucial for center facilitation while SST interneurons contribute preferentially to surround suppression — assigning distinct disinhibitory and inhibitory roles to VIP vs SST in cortical attention.
- raw_fields
{
"n": null,
"doi": "10.1126/science.1254126",
"claim": "Long-range cingulate→V1 projections act through local GABAergic circuits to produce spatially structured top-down modulation: VIP interneurons are crucial for center facilitation while SST interneurons contribute preferentially to surround suppression — assigning distinct disinhibitory and inhibitory roles to VIP vs SST in cortical attention.",
"title": null,
"cite_key": "Zhang2014",
"evidence": "Optogenetic activation of cingulate→V1 axons + cell-type-specific perturbation of VIP and SST interneurons; visual-discrimination behavior.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "mouse Cg→V1 optogenetics + behavior",
"target_section": "section_05",
"_source_cluster": "cluster_01_molecular_taxonomy",
"replication_status": "single_study",
"_source_cluster_index": 72,
"claim_source_sentence": "Whereas somatostatin-positive GABAergic interneurons contributed preferentially to surround suppression, vasoactive intestinal peptide-positive interneurons were crucial for center facilitation."
}- source_refs
[
"paper:paper-05bd6c97da43"
]
- evidence_refs
[
{
"ref": "paper:paper-05bd6c97da43"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}