- claim_text
Patch-seq combined with viral targeting of GABAergic subclasses in human neocortex reveals transitions between PVALB and SST subclasses and identifies primate-specialized double bouquet cell types, highlighting cellular differences between homologous mouse and human cortical GABAergic neurons.
- raw_fields
{
"n": 0,
"doi": "10.1126/science.adf6484",
"claim": "Patch-seq combined with viral targeting of GABAergic subclasses in human neocortex reveals transitions between PVALB and SST subclasses and identifies primate-specialized double bouquet cell types, highlighting cellular differences between homologous mouse and human cortical GABAergic neurons.",
"cite_key": "Lee2023",
"evidence": "Patch-seq applied at scale in human cortex to refine transcriptomic taxonomies — relevant to scaling and cross-species comparability discussion in cluster_14.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "Human neocortex Patch-seq",
"argument_role": "supporting",
"replication_status": "single-study",
"claim_source_sentence": "Rapid GABAergic neuron viral genetic labeling plus Patch-seq (patch-clamp electrophysiology plus single-cell RNA sequencing) sampling in human brain slices was used to reliably target and analyze GABAergic neuron subclasses and individual transcriptomic types.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-37824669",
"paper:paper-430f33cd589f"
]
- source_span
Rapid GABAergic neuron viral genetic labeling plus Patch-seq (patch-clamp electrophysiology plus single-cell RNA sequencing) sampling in human brain slices was used to reliably target and analyze GABAergic neuron subclasses and individual transcriptomic types.
- evidence_refs
[
{
"ref": "paper:paper-37824669"
},
{
"ref": "paper:paper-430f33cd589f"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}