- claim_text
Sox6 is expressed continuously in MGE-derived cortical interneurons from postmitotic progenitor stages into adulthood and acts downstream of Lhx6 to control PV/SST positioning and maturation; its loss preserves immature fast-spiking properties of basket cells and produces severe epileptic encephalopathy.
- raw_fields
{
"n": 0,
"doi": "10.1016/j.neuron.2009.08.005",
"claim": "Sox6 is expressed continuously in MGE-derived cortical interneurons from postmitotic progenitor stages into adulthood and acts downstream of Lhx6 to control PV/SST positioning and maturation; its loss preserves immature fast-spiking properties of basket cells and produces severe epileptic encephalopathy.",
"title": null,
"cite_key": "Batistabrito2009",
"evidence": "Mouse genetics, immunohistochemistry, and patch-clamp electrophysiology of basket cells in Sox6 conditional knockouts.",
"effect_size": "qualitative",
"text_access": "abstract_only",
"study_system": "mouse (Sox6 conditional knockout)",
"_source_cluster": "cluster_02_development_lineage",
"replication_status": "replication_unknown",
"_source_cluster_index": 42,
"claim_source_sentence": "We identify Sox6 as a protein expressed continuously within MGE-derived cortical interneurons from postmitotic progenitor stages into adulthood.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-25b49fc200d0"
]
- evidence_refs
[
{
"ref": "paper:paper-25b49fc200d0"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}