Bursting VIP+ neurons in mouse barrel cortex are confined to layer II/III; laye…

{
  "n": null,
  "doi": "10.1093/cercor/bhv202",
  "claim": "Bursting VIP+ neurons in mouse barrel cortex are confined to layer II/III; layers IV–VI lack bursting VIP+ cells while still expressing IS (14.7%) and HTBNA (2.9%) variants alongside the dominant CA (82.4%) firing pattern.",
  "title": null,
  "cite_key": "Pronneke2015",
  "evidence": "VIP-Cre/tdTomato whole-cell, layer-stratified analysis of firing-pattern frequencies; bursting cells observed only in L2/3",
  "effect_size": "L2/3 — CA 67.6%, IS 14.7%, bursting 11.8%, HTBNA 5.9%; L4–L6 — CA 82.4%, IS 14.7%, HTBNA 2.9%; bursting absent below L3",
  "text_access": "fulltext",
  "study_system": "mouse VIP-IRES-Cre × Ai14 barrel cortex; layer-by-layer firing-pattern survey",
  "_source_cluster": "cluster_04_intrinsic_electrophysiology",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 26,
  "claim_source_sentence": "In layers IV–VI, 82.4% of all VIP neurons were continuous adapting, 14.7% irregular spiking, and 2.9% high threshold bursting nonadapting.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "In layer II/III, 67.6% of all VIP neurons were continuous adapting, 14.7% irregular spiking, 11.8% bursting, and 5.9% high threshold bursting nonadapting."
}

[
  "paper:paper-8e91417bef90"
]

[
  {
    "ref": "paper:paper-8e91417bef90"
  }
]

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}