Details

scope
mouse VIP-IRES-Cre × Ai14 barrel cortex slices; whole-cell patch
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
effect_size
Rin 404.7 ± 212.8 MΩ; sag 11.2 ± 6.8%; τm 21.4 ± 7.6 ms; rheobase 51.9 ± 33.9 pA; AP threshold −38.2 ± 3.1 mV; AP amplitude 65.1 ± 9.1 mV (mean ± SD across layers)
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-05-electrophysiology
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
study_system
mouse VIP-IRES-Cre × Ai14 barrel cortex slices; whole-cell patch
section_title
Intrinsic Electrophysiology
evidence_summary
whole-cell current-clamp from VIP-Cre × Ai14 mouse barrel cortex; layer-by-layer comparisons performed with biocytin reconstructions
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-05-electrophysiology
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
claim_text
Across all cortical layers in mouse barrel cortex VIP-Cre/tdTomato neurons, the population mean intrinsic properties are: input resistance 404.7 ± 212.8 MΩ, sag index 11.2 ± 6.8%, membrane time constant 21.4 ± 7.6 ms, rheobase 51.9 ± 33.9 pA, AP threshold −38.2 ± 3.1 mV, AP amplitude 65.1 ± 9.1 mV.
raw_fields
{
  "n": null,
  "doi": "10.1093/cercor/bhv202",
  "claim": "Across all cortical layers in mouse barrel cortex VIP-Cre/tdTomato neurons, the population mean intrinsic properties are: input resistance 404.7 ± 212.8 MΩ, sag index 11.2 ± 6.8%, membrane time constant 21.4 ± 7.6 ms, rheobase 51.9 ± 33.9 pA, AP threshold −38.2 ± 3.1 mV, AP amplitude 65.1 ± 9.1 mV.",
  "title": null,
  "cite_key": "Pronneke2015",
  "evidence": "whole-cell current-clamp from VIP-Cre × Ai14 mouse barrel cortex; layer-by-layer comparisons performed with biocytin reconstructions",
  "effect_size": "Rin 404.7 ± 212.8 MΩ; sag 11.2 ± 6.8%; τm 21.4 ± 7.6 ms; rheobase 51.9 ± 33.9 pA; AP threshold −38.2 ± 3.1 mV; AP amplitude 65.1 ± 9.1 mV (mean ± SD across layers)",
  "text_access": "fulltext",
  "study_system": "mouse VIP-IRES-Cre × Ai14 barrel cortex slices; whole-cell patch",
  "_source_cluster": "cluster_04_intrinsic_electrophysiology",
  "replication_status": "replicated",
  "_source_cluster_index": 24,
  "claim_source_sentence": "No significant differences were found in most of the basic properties such as in input resistance (population average of 404.7 ± 212.8 MΩ), sag index (11.2 ± 6.8%), τ (21.4 ± 7.6 ms), rheobase (51.9 ± 33.9 pA), firing threshold (−38.2 ± 3.1 mV), amplitude of action potentials (65.1 ± 9.1 mV), rise t...",
  "replication_evidence_dois": [
    "10.1093/cercor/bhw143",
    "10.1523/jneurosci.17-10-03894.1997"
  ],
  "effect_size_source_sentence": "input resistance (population average of 404.7 ± 212.8 MΩ), sag index (11.2 ± 6.8%), τ (21.4 ± 7.6 ms), rheobase (51.9 ± 33.9 pA), firing threshold (−38.2 ± 3.1 mV), amplitude of action potentials (65.1 ± 9.1 mV)"
}
source_refs
[
  "paper:paper-8e91417bef90"
]
source_span
No significant differences were found in most of the basic properties such as in input resistance (population average of 404.7 ± 212.8 MΩ), sag index (11.2 ± 6.8%), τ (21.4 ± 7.6 ms), rheobase (51.9 ± 33.9 pA), firing threshold (−38.2 ± 3.1 mV), amplitude of action potentials (65.1 ± 9.1 mV), rise t...
evidence_refs
[
  {
    "ref": "paper:paper-8e91417bef90"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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