Details

scope
human and primate Parkinson's disease
claim_text
Multiple unexplained features of Parkinson's disease pathophysiology (gait, postural control, axial signs) are inadequately captured by the strict rate-based direct/indirect pathway model and require pattern- and synchrony-based extensions
section_id
section_04
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json
effect_size
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-04
source_kind
review_finding
source_path
evidence/section_04_evidence_package.json
source_span
The pathophysiology of Parkinson's disease is reviewed in light of recent advances in the understanding of the functional organization of the basal ganglia (BG).
study_system
human and primate Parkinson's disease
section_title
Striatal Output Pathways: Direct, Indirect, and Beyond
evidence_summary
Narrative review of clinical and physiological data inconsistent with the classical Albin/DeLong rate model
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-04
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1002/ana.21481",
  "claim": "Multiple unexplained features of Parkinson's disease pathophysiology (gait, postural control, axial signs) are inadequately captured by the strict rate-based direct/indirect pathway model and require pattern- and synchrony-based extensions",
  "cite_key": "Obeso2009",
  "evidence": "Narrative review of clinical and physiological data inconsistent with the classical Albin/DeLong rate model",
  "effect_size": "",
  "text_access": "abstract_only",
  "study_system": "human and primate Parkinson's disease",
  "source_cluster_id": "cluster_04",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "The pathophysiology of Parkinson's disease is reviewed in light of recent advances in the understanding of the functional organization of the basal ganglia (BG).",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-adc7d0b761ee"
]
evidence_refs
[
  {
    "ref": "paper:paper-adc7d0b761ee"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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