- claim_text
Cortical interneuron specification is driven by transcription factors operating at successive developmental stages, but extrinsic signals also influence fate, indicating an interplay between cell-intrinsic genetic programs and environmental cues.
- raw_fields
{
"n": 0,
"doi": "10.1016/j.conb.2013.12.012",
"claim": "Cortical interneuron specification is driven by transcription factors operating at successive developmental stages, but extrinsic signals also influence fate, indicating an interplay between cell-intrinsic genetic programs and environmental cues.",
"title": null,
"cite_key": "Kessaris2014",
"evidence": "Synthesis of work mapping TF cascades and extrinsic-signal modulation in interneuron specification.",
"effect_size": "qualitative",
"text_access": "abstract_only",
"study_system": "review (rodent)",
"_source_cluster": "cluster_02_development_lineage",
"replication_status": "replication_unknown",
"_source_cluster_index": 62,
"claim_source_sentence": "As genetic programs are influenced by external factors the search continues not only into genetic determinants but also extrinsic influences and the interplay between the two in cell fate specification.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-5f47072d0435"
]
- evidence_refs
[
{
"ref": "paper:paper-5f47072d0435"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}