Details

scope
mouse, BLA-mPFC, optogenetics + behavior
claim_text
Optogenetic stimulation of PV interneurons in BLA at 4Hz and 8Hz exerts bidirectional control over conditioned freezing in experience- and context-specific manner
section_id
section_08_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
effect_size
bidirectional control of freezing by 4Hz vs 8Hz BLA oscillations
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-08
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
source_span
exogenously induced 4 Hz and 8 Hz oscillatory activity in the BLA exerts bi-directional control over conditioned freezing behavior in an experience- and context-specific manner
study_system
mouse, BLA-mPFC, optogenetics + behavior
section_title
In Vivo Dynamics and Behavioural Correlates
evidence_summary
4Hz resonance across BLA-mPFC circuitry supports post-extinction fear memory retrieval; oscillations have experience-dependent ability to recruit distinct functional neuronal ensembles
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-08
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1038/s41467-020-18199-w",
  "claim": "Optogenetic stimulation of PV interneurons in BLA at 4Hz and 8Hz exerts bidirectional control over conditioned freezing in experience- and context-specific manner",
  "evidence": "4Hz resonance across BLA-mPFC circuitry supports post-extinction fear memory retrieval; oscillations have experience-dependent ability to recruit distinct functional neuronal ensembles",
  "effect_size": "bidirectional control of freezing by 4Hz vs 8Hz BLA oscillations",
  "text_access": "fulltext",
  "study_system": "mouse, BLA-mPFC, optogenetics + behavior",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "exogenously induced 4 Hz and 8 Hz oscillatory activity in the BLA exerts bi-directional control over conditioned freezing behavior in an experience- and context-specific manner",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "exogenously induced 4 Hz and 8 Hz oscillatory activity in the BLA exerts bi-directional control over conditioned freezing behavior"
}
source_refs
[
  "paper:paper-76b9ba0db913"
]
evidence_refs
[
  {
    "ref": "paper:paper-76b9ba0db913"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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