Head-direction tuning in mouse anterior dorsal thalamus remains stable and robu…

Head-direction tuning in mouse anterior dorsal thalamus remains stable and robust in congenitally degenerated and adult-blind rd1 mice, with the HD attractor network remaining intact in the absence of both visual and olfactory cues but with preferred firing direction drifting over time — consistent with an internal continuous-attractor architecture anchored, but not generated, by external cues.

{
  "n": 0,
  "doi": "10.1038/s41467-022-33204-0",
  "claim": "Head-direction tuning in mouse anterior dorsal thalamus remains stable and robust in congenitally degenerated and adult-blind rd1 mice, with the HD attractor network remaining intact in the absence of both visual and olfactory cues but with preferred firing direction drifting over time — consistent with an internal continuous-attractor architecture anchored, but not generated, by external cues.",
  "cite_key": "Asumbisa2022",
  "evidence": "",
  "effect_size": "",
  "text_access": "abstract_only",
  "study_system": "mouse anterior dorsal thalamus HD cells in rd1 (blind) and sighted mice with manipulated sensory cues",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Finally, in the absence of both visual and olfactory cues, the HD attractor network remains intact but the preferred firing direction of HD cells drifts over time.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1038/s41467-020-15566-5"
  ],
  "effect_size_source_sentence": null
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