Details
- scope
- review of mouse cortical interneuron development
- section_id
- section_03
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
- effect_size
- up to ~50 cortical interneuron types proposed
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-03-development
- source_kind
- review_finding
- source_path
- evidence/section_03_evidence_package.json
- source_span
- Interneuron diversity seems to emerge through the implementation of cell-intrinsic genetic programs in progenitor cells, which unfold over a protracted period of time until interneurons acquire mature characteristics.
- study_system
- review of mouse cortical interneuron development
- section_title
- Developmental Origins and Postnatal Maturation
- evidence_summary
- Synthesis review covering subpallial origin, transcriptional specification, migration, and activity-dependent integration of cortical interneurons.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-03-development
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- claim_text
Cortical GABAergic interneuron diversity emerges from cell-intrinsic genetic programs in subpallial progenitors that unfold over a protracted period and are subsequently modulated by activity-dependent, non-cell-autonomous mechanisms during circuit integration.
- raw_fields
{ "n": 0, "doi": "10.1016/j.neuron.2018.10.009", "claim": "Cortical GABAergic interneuron diversity emerges from cell-intrinsic genetic programs in subpallial progenitors that unfold over a protracted period and are subsequently modulated by activity-dependent, non-cell-autonomous mechanisms during circuit integration.", "title": null, "cite_key": "Lim2018", "evidence": "Synthesis review covering subpallial origin, transcriptional specification, migration, and activity-dependent integration of cortical interneurons.", "effect_size": "up to ~50 cortical interneuron types proposed", "text_access": "abstract_only", "study_system": "review of mouse cortical interneuron development", "_source_cluster": "cluster_02_development_lineage", "replication_status": "replication_unknown", "_source_cluster_index": 46, "claim_source_sentence": "Interneuron diversity seems to emerge through the implementation of cell-intrinsic genetic programs in progenitor cells, which unfold over a protracted period of time until interneurons acquire mature characteristics.", "replication_evidence_dois": [], "effect_size_source_sentence": "Current estimates suggest that up to 50 different types of GABAergic neurons may populate the cerebral cortex, all derived from progenitor cells in the subpallium, the ventral aspect of the embryonic telencephalon." }- source_refs
[ "paper:paper-11e0bb0a904f" ]
- evidence_refs
[ { "ref": "paper:paper-11e0bb0a904f" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }