Details

scope
mouse primary visual cortex (V1), MAPseq
claim_text
MAPseq barcoded axonal tracing of 591 individual mouse V1 projection neurons reveals that single excitatory neurons frequently distribute their output across multiple cortical and subcortical targets rather than projecting to a single area.
section_id
section_01
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-01-introduction
source_kind
review_finding
source_path
evidence/section_01_evidence_package.json
source_span
Here we determine the projection patterns of 591 individual neurons in the mouse primary visual cortex using whole-brain fluorescence-based axonal tracing and high-throughput DNA sequencing of genetically barcoded neurons (MAPseq).
study_system
mouse primary visual cortex (V1), MAPseq
section_title
1. Introduction — what "excitatory recurrence" means operationally in mouse cortex, and why isolating it from inhibition and from clinical framings is a defensible analytic move for basic-research synthesis
evidence_summary
MAPseq barcoded RNA tracing of single neurons in mouse V1, with whole-brain axonal mapping.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-01-introduction
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": "591 neurons",
  "doi": "10.1038/nature26159",
  "claim": "MAPseq barcoded axonal tracing of 591 individual mouse V1 projection neurons reveals that single excitatory neurons frequently distribute their output across multiple cortical and subcortical targets rather than projecting to a single area.",
  "cite_key": "Han2018",
  "evidence": "MAPseq barcoded RNA tracing of single neurons in mouse V1, with whole-brain axonal mapping.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "mouse primary visual cortex (V1), MAPseq",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Here we determine the projection patterns of 591 individual neurons in the mouse primary visual cortex using whole-brain fluorescence-based axonal tracing and high-throughput DNA sequencing of genetically barcoded neurons (MAPseq).",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-236d0f50c2dd"
]
evidence_refs
[
  {
    "ref": "paper:paper-236d0f50c2dd"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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