Details
- scope
- mouse primary visual cortex (V1), 2p optogenetics, slice
- section_id
- section_01
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
- effect_size
- 30,454 candidate inputs probed; 1,790 confirmed E inputs
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-01-introduction
- source_kind
- review_finding
- source_path
- evidence/section_01_evidence_package.json
- source_span
- For pyramidal cells, optomapping reproduced the canonical circuit but unexpectedly uncovered that the excitation of basket cells concentrated to layer 5 and that of Martinotti cells dominated in layer 2/3.
- study_system
- mouse primary visual cortex (V1), 2p optogenetics, slice
- section_title
- 1. Introduction — what "excitatory recurrence" means operationally in mouse cortex, and why isolating it from inhibition and from clinical framings is a defensible analytic move for basic-research synthesis
- evidence_summary
- Two-photon 'optomapping' in mouse V1 sampling 30,454 candidate presynaptic locations and 1,790 confirmed excitatory inputs onto identified postsynaptic cell types.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-01-introduction
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- claim_text
Across pyramidal, basket, and Martinotti cells in mouse V1 mapped with two-photon optogenetics, excitatory input efficacies follow a log-normal distribution, with E→PV-basket inputs concentrated in layer 5 and E→Martinotti excitation strongest in L2/3.
- raw_fields
{ "n": null, "doi": "10.1016/j.xinn.2024.100735", "claim": "Across pyramidal, basket, and Martinotti cells in mouse V1 mapped with two-photon optogenetics, excitatory input efficacies follow a log-normal distribution, with E→PV-basket inputs concentrated in layer 5 and E→Martinotti excitation strongest in L2/3.", "cite_key": "Chou2025", "evidence": "Two-photon 'optomapping' in mouse V1 sampling 30,454 candidate presynaptic locations and 1,790 confirmed excitatory inputs onto identified postsynaptic cell types.", "effect_size": "30,454 candidate inputs probed; 1,790 confirmed E inputs", "text_access": "abstract_only", "study_system": "mouse primary visual cortex (V1), 2p optogenetics, slice", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "For pyramidal cells, optomapping reproduced the canonical circuit but unexpectedly uncovered that the excitation of basket cells concentrated to layer 5 and that of Martinotti cells dominated in layer 2/3.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "In mouse primary visual cortex (V1), we optomapped 30,454 candidate inputs to reveal 1,790 excitatory inputs to pyramidal, basket, and Martinotti cells." }- source_refs
[ "paper:paper-20192df165b8" ]
- evidence_refs
[ { "ref": "paper:paper-20192df165b8" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }