Details

scope
human MTG L1 (snRNA-seq) vs. mouse L1 literature
section_id
section_03
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
effect_size
Human L1 contains CGE-derived SST+ types; mouse L1 lacks SST+ interneurons
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-03-development
source_kind
review_finding
source_path
evidence/section_03_evidence_package.json
source_span
Some CGE-derived cell types in L1 expressed SST ( Fig. 3a , c ), as described in human 14 but not in mouse L1 interneurons 22 .
study_system
human MTG L1 (snRNA-seq) vs. mouse L1 literature
section_title
Developmental Origins and Postnatal Maturation
evidence_summary
snRNA-seq of human MTG with layer-dissected nuclei; SST expression in CGE-derived (ADARB2-branch) L1 types; cross-reference to prior human histological studies.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
primary
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-03-development
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
Some CGE-derived cell types in human cortical layer 1 express SST (somatostatin), a feature not seen in mouse layer 1 interneurons — providing a primate/human-specific anatomical-molecular feature distinguishing CGE-derived interneurons from rodents.
raw_fields
{
  "n": null,
  "doi": "10.1038/s41586-019-1506-7",
  "claim": "Some CGE-derived cell types in human cortical layer 1 express SST (somatostatin), a feature not seen in mouse layer 1 interneurons — providing a primate/human-specific anatomical-molecular feature distinguishing CGE-derived interneurons from rodents.",
  "title": null,
  "cite_key": "Hodge2019",
  "evidence": "snRNA-seq of human MTG with layer-dissected nuclei; SST expression in CGE-derived (ADARB2-branch) L1 types; cross-reference to prior human histological studies.",
  "effect_size": "Human L1 contains CGE-derived SST+ types; mouse L1 lacks SST+ interneurons",
  "figure_data": [],
  "text_access": "fulltext",
  "study_system": "human MTG L1 (snRNA-seq) vs. mouse L1 literature",
  "_source_cluster": "cluster_02_development_lineage",
  "replication_status": "primary",
  "_source_cluster_index": 102,
  "claim_source_sentence": "Some CGE-derived cell types in L1 expressed SST ( Fig. 3a , c ), as described in human 14 but not in mouse L1 interneurons 22 .",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Some CGE-derived cell types in L1 expressed SST ( Fig. 3a , c ), as described in human 14 but not in mouse L1 interneurons 22 ."
}
source_refs
[
  "paper:paper-pm-31435019"
]
evidence_refs
[
  {
    "ref": "paper:paper-pm-31435019"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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