- raw_fields
{
"n": null,
"doi": "10.1016/j.isci.2021.102450",
"claim": "[mouse] Such organization of feedback projections to V1 suggests that parts of the visual field are differentially modulated by context, which can be ethologically relevant for a navigating animal.",
"cite_key": "Morimoto2021",
"evidence": "Top-down, context-dependent modulation of visual processing has been a topic of wide interest, including in mouse primary visual cortex (V1). However, the organization of feedback projections to V1 is relatively unknown. Here, we investigated inputs to mouse V1 by injecting retrograde tracers. We developed a software pipeline that maps labeled cell bodies to corresponding brain areas in the Allen Reference Atlas. We identified more than 24 brain areas that provide inputs to V1 and quantified the...",
"effect_size": "The relative percentage of supragranular (superficial layer) labeled neurons (%SLN) have been described to correlate with hierarchy of cortical areas in primates (), where a %SLN lower than 50% is considered higher in hierarchy than the target region and thus providing feedback inputs.",
"text_access": "fulltext",
"study_system": "mouse; V1, visual cortex; iScience",
"argument_role": "supporting",
"replication_status": "single_study",
"claim_source_sentence": "Such organization of feedback projections to V1 suggests that parts of the visual field are differentially modulated by context, which can be ethologically relevant for a navigating animal.",
"source_provenance_status": "ok",
"replication_evidence_dois": [],
"claim_rewritten_from_source": true,
"effect_size_source_sentence": "The relative percentage of supragranular (superficial layer) labeled neurons (%SLN) have been described to correlate with hierarchy of cortical areas in primates (), where a %SLN lower than 50% is considered higher in hierarchy than the target region and thus providing feedback inputs."
}- effect_size
The relative percentage of supragranular (superficial layer) labeled neurons (%SLN) have been described to correlate with hierarchy of cortical areas in primates (), where a %SLN lower than 50% is considered higher in hierarchy than the target region and thus providing feedback inputs.
- source_refs
[
"paper:paper-d7b1ce6b8616"
]
- evidence_refs
[
{
"ref": "paper:paper-d7b1ce6b8616"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}- evidence_summary
Top-down, context-dependent modulation of visual processing has been a topic of wide interest, including in mouse primary visual cortex (V1). However, the organization of feedback projections to V1 is relatively unknown. Here, we investigated inputs to mouse V1 by injecting retrograde tracers. We developed a software pipeline that maps labeled cell bodies to corresponding brain areas in the Allen Reference Atlas. We identified more than 24 brain areas that provide inputs to V1 and quantified the...