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"n": null,
"doi": "10.1016/j.neuron.2023.11.006",
"claim": "[mouse] Circuit modeling revealed a precise network architecture consistent with multiplexing strong yet non-interacting modulations in the same neural population.",
"cite_key": "MyersJoseph2024",
"evidence": "Attentional modulation of sensory processing is a key feature of cognition; however, its neural circuit basis is poorly understood. A candidate mechanism is the disinhibition of pyramidal cells through vasoactive intestinal peptide (VIP) and somatostatin (SOM)-positive interneurons. However, the interaction of attentional modulation and VIP-SOM disinhibition has never been directly tested. We used all-optical methods to bi-directionally manipulate VIP interneuron activity as mice performed a cro...",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "mouse; V1, visual cortex; computational model; Neuron",
"argument_role": "supporting",
"replication_status": "single_study",
"claim_source_sentence": "Circuit modeling revealed a precise network architecture consistent with multiplexing strong yet non-interacting modulations in the same neural population.",
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],
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Attentional modulation of sensory processing is a key feature of cognition; however, its neural circuit basis is poorly understood. A candidate mechanism is the disinhibition of pyramidal cells through vasoactive intestinal peptide (VIP) and somatostatin (SOM)-positive interneurons. However, the interaction of attentional modulation and VIP-SOM disinhibition has never been directly tested. We used all-optical methods to bi-directionally manipulate VIP interneuron activity as mice performed a cro...