Details

scope
mouse; motor cortex; The Journal of neuroscience : the official journal of the Society for Neuroscience
claim_text
The motor cortex fine-tunes preparatory activity for more accurate movement using the predictability of go timing.
section_id
section_09
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-09-amplification-isn
source_kind
review_finding
source_path
evidence/section_09_evidence_package.json
source_span
Our results suggest that the motor cortex fine-tunes preparatory activity for more accurate movement using the predictability of go timing.
study_system
mouse; motor cortex; The Journal of neuroscience : the official journal of the Society for Neuroscience
section_title
9. Physiological signature I — recurrent amplification of weak inputs in mouse cortex; balanced-amplification regimes; ISN operation
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single_study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-09-amplification-isn
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
raw_fields
{
  "n": null,
  "doi": "10.1523/jneurosci.1353-23.2024",
  "claim": "The motor cortex fine-tunes preparatory activity for more accurate movement using the predictability of go timing.",
  "cite_key": "Chae2024",
  "evidence": "The motor cortex not only executes but also prepares movement, as motor cortical neurons exhibit preparatory activity that predicts upcoming movements. In movement preparation, animals adopt different strategies in response to uncertainties existing in nature such as the unknown timing of when a predator will attack-an environmental cue informing \"go.\" However, how motor cortical neurons cope with such uncertainties is less understood. In this study, we aim to investigate whether and how prepara...",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse; motor cortex; The Journal of neuroscience : the official journal of the Society for Neuroscience",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "Our results suggest that the motor cortex fine-tunes preparatory activity for more accurate movement using the predictability of go timing.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "claim_rewritten_from_source": true,
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-8c2ddb1bda78"
]
evidence_refs
[
  {
    "ref": "paper:paper-8c2ddb1bda78"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}
evidence_summary
The motor cortex not only executes but also prepares movement, as motor cortical neurons exhibit preparatory activity that predicts upcoming movements. In movement preparation, animals adopt different strategies in response to uncertainties existing in nature such as the unknown timing of when a predator will attack-an environmental cue informing "go." However, how motor cortical neurons cope with such uncertainties is less understood. In this study, we aim to investigate whether and how prepara...

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