Details

scope
Mouse (C57BL/6J); Allen anterograde tracer data
claim_text
A 100 µm voxel-resolution data-driven model of the mouse mesoscale connectome built from Allen tracer data outperforms region-level models in predicting held-out experiments.
section_id
section_08
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
effect_size
428 anterograde experiments; ~2×10^5 source voxels; voxel model outperforms regional baseline (qualitative)
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
source_span
The voxel model outperforms a previous regional model in predicting held-out experiments and compared with a human-curated dataset.
study_system
Mouse (C57BL/6J); Allen anterograde tracer data
section_title
8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views
evidence_summary
Voxel-scale radial-basis kernel model fit to 428 anterograde tracing experiments in wild-type C57BL/6J mice, predicting held-out injections; comparison to a region-level connectome.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single-study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": 428,
  "doi": "10.1162/netn_a_00066",
  "claim": "A 100 µm voxel-resolution data-driven model of the mouse mesoscale connectome built from Allen tracer data outperforms region-level models in predicting held-out experiments.",
  "cite_key": "Knox2019",
  "evidence": "Voxel-scale radial-basis kernel model fit to 428 anterograde tracing experiments in wild-type C57BL/6J mice, predicting held-out injections; comparison to a region-level connectome.",
  "effect_size": "428 anterograde experiments; ~2×10^5 source voxels; voxel model outperforms regional baseline (qualitative)",
  "text_access": "abstract_only",
  "study_system": "Mouse (C57BL/6J); Allen anterograde tracer data",
  "argument_role": "supporting",
  "replication_status": "single-study",
  "claim_source_sentence": "The voxel model outperforms a previous regional model in predicting held-out experiments and compared with a human-curated dataset.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "The data consist of 428 anterograde tracing experiments in wild type C57BL/6J mice, mapping fluorescently labeled neuronal projections brain-wide."
}
source_refs
[
  "paper:paper-f5e9a71430d3"
]
evidence_refs
[
  {
    "ref": "paper:paper-f5e9a71430d3"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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