Retrograde tract-tracing of 19 mouse cortical areas (27 injections) reveals a l…

Retrograde tract-tracing of 19 mouse cortical areas (27 injections) reveals a log-normal weighted cortical connection distribution spanning ~5 orders of magnitude and an ultra-dense inter-areal graph with 97% binary density — substantially denser than the 66% reported for macaque.

{
  "n": 27,
  "doi": "10.1016/j.neuron.2017.12.037",
  "claim": "Retrograde tract-tracing of 19 mouse cortical areas (27 injections) reveals a log-normal weighted cortical connection distribution spanning ~5 orders of magnitude and an ultra-dense inter-areal graph with 97% binary density — substantially denser than the 66% reported for macaque.",
  "cite_key": "Gamanut2018",
  "evidence": "Twenty-seven retrograde tracer injections in 19 of 47 parcellated mouse cortical areas; flat-mount histology with multiple markers; weighted graph analysis.",
  "effect_size": "97% binary density (mouse) vs 66% (macaque); weight distribution spans 5 orders of magnitude.",
  "text_access": "abstract_only",
  "study_system": "Mouse neocortex, retrograde tract tracing in 19/47 parcellated areas",
  "argument_role": "supporting",
  "replication_status": "replicated",
  "claim_source_sentence": "The observed log-normal distribution of connection weights to each cortical area spans 5 orders of magnitude and reveals a distinct connectivity profile for each area, analogous to that observed in macaques.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1162/netn_a_00345"
  ],
  "effect_size_source_sentence": "The cortical network has a density of 97%, considerably higher than the 66% density reported in macaques."
}

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