Details

scope
Mouse M1, layer-5 deep output neurons; rabies tracing + optogenetics
claim_text
Long-range monosynaptic inputs to mouse M1 layer-5 deep output neurons co-innervate both apical and basal dendritic compartments, arising from spatially segregated subpopulations within each upstream area.
section_id
section_08
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
effect_size
Dual-compartment innervation by most upstream areas; segregated subpopulations even within a single cortical layer (qualitative).
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
source_span
We revealed that most upstream areas innervate both dendritic compartments concurrently.
study_system
Mouse M1, layer-5 deep output neurons; rabies tracing + optogenetics
section_title
8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views
evidence_summary
Cre-dependent rabies tracing combined with layer-specific retrograde labeling, optogenetics, and slice recording for M1 L5 deep output neurons in mouse.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single-study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1093/cercor/bhab460",
  "claim": "Long-range monosynaptic inputs to mouse M1 layer-5 deep output neurons co-innervate both apical and basal dendritic compartments, arising from spatially segregated subpopulations within each upstream area.",
  "cite_key": "Geng2022",
  "evidence": "Cre-dependent rabies tracing combined with layer-specific retrograde labeling, optogenetics, and slice recording for M1 L5 deep output neurons in mouse.",
  "effect_size": "Dual-compartment innervation by most upstream areas; segregated subpopulations even within a single cortical layer (qualitative).",
  "text_access": "abstract_only",
  "study_system": "Mouse M1, layer-5 deep output neurons; rabies tracing + optogenetics",
  "argument_role": "supporting",
  "replication_status": "single-study",
  "claim_source_sentence": "We revealed that most upstream areas innervate both dendritic compartments concurrently.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Furthermore, the dichotomous inputs arise mostly from spatially segregated neuronal subpopulations within an upstream nucleus, and even in the case of an individual cortical layer."
}
source_refs
[
  "paper:paper-628d4113d368"
]
evidence_refs
[
  {
    "ref": "paper:paper-628d4113d368"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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